ABSTRACT
Reports on studies devoted entirely to the results of electroencephalographic recordings in phacomatosis are not available, and the authors review the large number of cases found throughout the published literature. Based on the information obtained and the results of their personal experience, they summarize the clinical findings, characteristic anomalies, and E.E.G. changes in tuberous sclerosis, neurofibromatosis, Sturge-Weber and von Hippel-Lindau diseases, and ataxia telangiectasia. Electroencephalographic studies can contribute to the diagnosis and follow-up of these affections.
Subject(s)
Angiomatosis/diagnosis , Electroencephalography , Neurofibromatosis 1/diagnosis , Sturge-Weber Syndrome/diagnosis , Tuberous Sclerosis/diagnosis , Adult , Ataxia Telangiectasia/diagnosis , Child , Diagnosis, Differential , Female , Humans , Infant , Male , von Hippel-Lindau Disease/diagnosisABSTRACT
The authors report on infectious-allergic encephalopathy, occurring in a nine-year old boy. The clinical picture is that of a generalized myoclonic epileptic state. The EEG shows bilaterally occurring stereotyped rhythmic complexes with a short interval. The child recovered completely. The diagnostic value of periodically occurring EEG-features and the familial occurrence of para-infectious encephalopathies are discussed.
Subject(s)
Electroencephalography , Encephalitis, Arbovirus/diagnosis , Child , Child, Preschool , Encephalitis, Arbovirus/complications , Encephalitis, Arbovirus/genetics , Epilepsy/etiology , Female , Humans , Male , PedigreeABSTRACT
The clinical and electroencephalographic observations in two patients with verified necrotising herpes-encephalitis are presented. In one of the ill persons it was possible to isolate the virus. With these two observations four additional ones published previously are compaired electroencephalographically. Thereby the EEG reveal a certain variation in form and local distribution of periodic discharges (bursts) from relatively regularly recurring slow waves to stereotype periodicity complexes. Next an attempt is made to arrive at physiopathogenetic explanations for the EEG-changes by compairing the pathologico-anatomical findings of the six cases presented with those of ten more cases. The topographical distribution of the anatomical lesions in these inflammatory precesses seem to be of special importance for the occurence of the EEG-changes.
Subject(s)
Electroencephalography/methods , Encephalitis/diagnosis , Herpes Simplex/diagnosis , Periodicity , Acute Disease , Adult , Child , Child, Preschool , Encephalitis/physiopathology , Female , Herpes Simplex/physiopathology , Humans , Male , Middle Aged , NecrosisABSTRACT
The electroclinical and pathological features of two infantile cases of acute necrotizing herpetic encephalitis are reported. The distribution of the lesions has been compared with those observed in fourteen other cases including four with EEG records. Various electroencephalographic features have been recorded including repetitive slow spikes and periodic stereotyped paroxysmal discharges. The pathological data are interpreted to attempt unravelling the physiopathology of the EEG features.
Subject(s)
Encephalitis/diagnosis , Herpesviridae Infections/diagnosis , Adult , Autopsy , Brain/pathology , Child , Child, Preschool , Electroencephalography , Encephalitis/pathology , Female , Herpesviridae/isolation & purification , Humans , Male , Middle AgedSubject(s)
Brain Diseases/physiopathology , Electroencephalography , Lipidoses/physiopathology , Movement Disorders/physiopathology , Axons , Brain Diseases/genetics , Child , Child, Preschool , Female , Humans , Infant , Male , Movement Disorders/genetics , Muscular Diseases/physiopathology , Pantothenate Kinase-Associated Neurodegeneration/physiopathologyABSTRACT
After a short historical introduction, the author presents the actual state of our biological knowledge with special reference to the increase of gamma-globulines and measle anti-bodies in the serum as well as in the CSF. He insists upon the works which identified and isolated the measle anti-gene but which nevertheless cannot define a special form of measle encephalities. Two hypothesis (a) immunologic (b) viral, could give an explanation of the observed facts. The neuro-pathological modifications are then related to the EEG abnormalities, but htese relations do not give an entire explanation of the genesis of periodic paroxysmal eeg activities, which are so unusual. The reproduction of encephalitis in the hamster and the ferret, from cerebral biopsies and cell cultures give hopes of further progress in the understanding of the etiopathology and perhaps the therapy of the subacute sclerosing panencephalitis.
