ABSTRACT
It is the purpose of the study to outline the superiorities of combined anesthesia in 100 patients undergoing orthopaedic (25 cases) and orthopaedic surgery (75 cases) interventions. The average duration of the operation is 90 +/- 25 min, performed under continuous peripheral (40 patients) and central (60 patients) nerve block, using Propofol against the background of continuous i.v. infusion and spontaneous ventilation. Nerve block is done according to routinely adopted techniques. The initial infusion rate for propofol (Diprivan) is 5 +/- 1.3 mg/kg/h, followed by infusional rate securing sedation II-III degree according to Ramsey's scale (mean 4 +/- 1.2 mg/kg/h). In 92 per cent of patients the sedation level is estimated as very good. In 8 per cent switching over to TIVA (total intravenous anesthesia) is necessitated because of the incomplete nerve block. No cases of hypotension or other essential secondary effects are recorded. Subjectively the anesthesiological technique is accepted as very good by most of the patients.
Subject(s)
Anesthesia, Conduction , Anesthesia, Intravenous , Anesthesia, Local , Anesthetics, Intravenous/administration & dosage , Propofol/administration & dosage , Adolescent , Adult , Aged , Aged, 80 and over , Anesthetics, Intravenous/adverse effects , Humans , Middle Aged , Propofol/adverse effects , Time FactorsABSTRACT
Continued sedation has important practical implications on overcoming the physical and psychic stress which in turn, has important practical implications on the well-being of patients in conditions of intensive care unit. It is the purpose of the study to assess the quality and characteristics of sustained sedation with constant propofol (Diprivan) and fentanyl infusion. As a result of the study the inference is reached that sedation with Diprivan and fentanyl, administered as constant infusion, lends itself readily to control, and what is more, it is free of noteworthy side effects. To secure permanent sedation it is necessary to adapt the infusional rate to the clinical signs in compliance with the concrete patient and individual needs.
