ABSTRACT
A non-tumoral stenosis of the gastrointestinal tract (after rectum resection) was treated successfully with CO2 laser. The case was not suitable for classic surgical resection.
Subject(s)
Adenoma/surgery , Carcinoma in Situ/surgery , Laser Therapy , Rectal Neoplasms/surgery , Adenoma/pathology , Carbon Dioxide/therapeutic use , Carcinoma in Situ/pathology , Cicatrix/surgery , Colonoscopy , Female , Humans , Middle Aged , Postoperative Complications/diagnosis , Postoperative Complications/surgery , Rectal Neoplasms/pathologyABSTRACT
Based on the clinical pattern (case history, radiological, endoscopic and laboratory examinations) four stages of ulcerous stenoses are distinguished (stage I: subclinical; stage II: compensated; stage III: decompensated; stage IV; complete stenosis). Organ-preserving vagotomy is justified only in stages I and II, in which the motoric function and emptying of the stomach is not yet damaged. In stages III and IV resection is the operation of choice. This view is supported by the results of the authors.
Subject(s)
Duodenal Obstruction/surgery , Duodenal Ulcer/surgery , Adult , Aged , Female , Humans , Male , Middle Aged , Pylorus/surgery , Vagotomy, Proximal GastricABSTRACT
Analyzing the patient material of 506 patients with gastric resection, authors deal with the early complication of resection, its diagnosis and treatment. They review the complications, their frequency and mortality in their own material. After operations made for tumour, complications occurred more frequently than after interventions because of ulcer. Total mortality was 10.2%. In order to reduce mortality they call attention to the possible prevention of complications and their careful management.
Subject(s)
Postoperative Complications , Stomach/surgery , Anastomosis, Surgical/adverse effects , Cholestasis/etiology , Gastrectomy , Hemorrhage/etiology , Humans , Pancreatitis/etiology , Stomach Neoplasms/surgery , Stomach Ulcer/surgery , Time Factors , Wound HealingABSTRACT
ACTH release under the effect of median eminence extract (ME) was studied in both incubation and superfusion experiments. ACTH content of the incubation medium was measured by radioimmunoassay or by the corticosterone production of trypsinisolated adrenocortical cells. Dopamine at low concentration led to a slight increase of basal ACTH secretion, while at higher concentration failed to influence ACTH release. The dopamine agonist CB-154 produced a significant rise of ACTH secretion and augmented the ME extract-induced increase of pituitary ACTH release. Chlorpromazine and haloperidol suppressed basal ACTH secretion and inhibited the ME extract-induced release. The simultaneous administration of CB-154 and haloperidol into the incubation medium prevented the haloperidol-induced inhibition of ACTH release. The observations indicate that dopaminergic receptors play a role in the activation of CRF-induced ACTH secretion under in vitro experimental conditions.
Subject(s)
Adrenocorticotropic Hormone/metabolism , Corticosterone/metabolism , Corticotropin-Releasing Hormone/pharmacology , Pituitary Gland, Anterior/metabolism , Receptors, Dopamine/physiology , Adrenal Cortex/metabolism , Animals , Bromocriptine/pharmacology , Chlorpromazine/pharmacology , Drug Interactions , Haloperidol/pharmacology , In Vitro Techniques , Male , Pancreas , Rats , Tissue Extracts/pharmacologyABSTRACT
The electrolytic lesion of locus coeruleus reduced the hypothalamic noradrenaline (NE) content to 28% of the control values and resulted in a marked decrease of the plasma FSH level in ovariectomized rats before puberty. The local microinjection of 6-OH-dopamine into the locus coeruleus led to a reduction in the hypothalamic NE content to 21% of the control level and induced a decrease of the compensatory ovarian hypertrophy and that of the plasma FSH level. The electrolytic lesion of the locus coeruleus or the 6-OH-dopamine treatment failed to influence the plasma growth hormone (GH) level. The observations support the hypothesis that ventral noradrenergic projection is involved in controlling the pituitary FSH secretion.
