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1.
Synthesis and radiosensitizing properties of some 2-furancarboxylic acid derivatives.
Tulecki, J; Dudzinska-Usarewicz, J; Radola, P.
Pol J Pharmacol Pharm ; 37(5): 709-15, 1985.
Article in English | MEDLINE | ID: mdl-3832015

ABSTRACT

New S-2-furoyl-O-alkyldithiocarbonic anhydrides have been obtained by condensation of 2-furoyl chloride with potassium O-alkyl-dithiocarbonates. The toxicity and radiosensitizing activity of these compounds were determined.


Subject(s)
Furans/chemical synthesis , Radiation-Sensitizing Agents/chemical synthesis , Animals , Chemical Phenomena , Chemistry , Furans/pharmacology , Furans/toxicity , Lethal Dose 50 , Magnetic Resonance Spectroscopy , Male , Mice , Radiation-Sensitizing Agents/toxicity , Spectrophotometry, Infrared , Sulfides/chemical synthesis , Sulfides/pharmacology , Sulfides/toxicity
2.
Activity of enzymes participating in the synthesis and degradation of glucuronides in postirradiative disease.
Kozaryn, I; Chodera, A; Szczawinska, K; Cenajek, D; Radola, P.
Acta Physiol Pol ; 26(2): 189-96, 1975.
Article in English | MEDLINE | ID: mdl-807084

Subject(s)
Glucuronates/metabolism , Radiation Injuries, Experimental/enzymology , Animals , Glucuronidase/metabolism , Glucuronosyltransferase/metabolism , Male , Rats , Uridine Diphosphate Glucose Dehydrogenase/metabolism , Uridine Diphosphate Glucuronic Acid/metabolism
3.
[Photochemistry of photodynamic compounds. IV. Photolysis of sulfanilamide S-35 in aqueous solutions]. / Fotochemia zwiazków o dzialaniu fotodynamicznym. IV. Badanie fotolizy wodnego roztworu sulfanilamidu znakowanego atomem siarki S-35
Pawlaczyk, J; Radola, P; Turowska, W.
Acta Pol Pharm ; 32(2): 187-91, 1975.
Article in Polish | MEDLINE | ID: mdl-1136827

Subject(s)
Photolysis , Sulfanilamides/analysis , Chromatography, Paper , Photochemistry , Solutions , Sulfur Radioisotopes , Water
4.
[Photochemistry of photodynamic compounds. V. Kinetics of photolysis of S-35-sulfanilamide aqueous solutions]. / Fotochemia zwiazków o dzialaniu fotodynamiczynm. V. Kinetyka fotolizy sulfanilamidu znakowanego atomen siarki S35 w roztworze wodnym (SNA - S35)
Pawlaczyk, J; Radola, P; Turowska, W.
Acta Pol Pharm ; 32(4): 465-9, 1975.
Article in Polish | MEDLINE | ID: mdl-1163258

Subject(s)
Photolysis , Sulfanilamides , Kinetics , Solutions , Sulfur Radioisotopes , Water
5.
Effect of fractionated irradiation on the pharmacodynamics and pharmacokinetics of sodium salicylate.
Szczawinska, K; Cenajek, D; Chodera, A; Radola, P.
Acta Physiol Pol ; 25(4): 377-81, 1974.
Article in English | MEDLINE | ID: mdl-4413054

Subject(s)
Analgesia , Radiation Effects , Sodium Salicylate , Animals , Brain/metabolism , Female , Radiation Dosage , Rats , Sodium Salicylate/blood , Sodium Salicylate/metabolism , Sodium Salicylate/pharmacology , Sodium Salicylate/urine
6.
Pathomorphology of muscular trichinellosis in comparative histological, histochemical, ultrastructural, autoradiographic and immunofluorescent investigations.
Gabryel, P; Gustowska, L; Blotna, M; Kasprzak, K; Radola, P.
Wiad Parazytol ; 15(5): 655-7, 1969.
Article in English | MEDLINE | ID: mdl-4312727

Subject(s)
Muscular Diseases/pathology , Trichinellosis/pathology , Animals , Autoradiography , Basophils , Endoplasmic Reticulum/analysis , Fluorescent Antibody Technique , Glycogen/analysis , Histocytochemistry , Humans , Muscles/enzymology , Phosphoric Monoester Hydrolases/analysis , Trichinellosis/immunology
7.
An attempt at elucidating the harmful effect of diphtheria toxin on the brain (isotopic studies). II. Spread of 131-I-albumin in cat brain damaged by diphtheria toxin.
Kasprzak, K; Radola, P; Sosinski, E.
Pol Med J ; 8(6): 1384-90, 1969.
Article in English | MEDLINE | ID: mdl-5370558

Subject(s)
Brain Diseases/metabolism , Diphtheria Toxin/toxicity , Serum Albumin, Radio-Iodinated , Animals , Autoradiography , Blood-Brain Barrier , Brain Diseases/chemically induced , Brain Diseases/pathology , Cats , Diphtheria Toxin/administration & dosage , Injections , Injections, Intravenous , Time Factors
8.
[Attempt of explanation of the mechanism of cerebral damage by diphtheria toxin (isotope studies). II. Distribution of I-131-albumin in the brain tissue of cats infected by diphtheria toxin]. / Próba wyjasnienia mechanizmu dzialania uszkadzajacego toksyny bloniczej na mózg (badania izotopowe). II. Rozprzestrzenianie sie albuminy-J131 w tkance mózgowej kota uszkodzonej przez toksynae blonicza.
Kasprzak, K; Radola, P; Sosinski, E.
Patol Pol ; 20(1): 15-22, 1969.
Article in Polish | MEDLINE | ID: mdl-5194392

Subject(s)
Blood-Brain Barrier , Brain Diseases/chemically induced , Diphtheria Toxin/toxicity , Serum Albumin, Radio-Iodinated , Animals , Autoradiography , Brain Edema/chemically induced , Cats
9.
[Binding of N,N'-bis (thiazole)-2,7-fluorenedisulfonamide-S-35 by serum proteins in cases of malignant tumors]. / Wiazanie sie N,N'-bis(tiazolo)-2,7-fluorenodwusulfonamidu-S-35 z bialkami surowicy krwi w przypadkach choroby nowotworowej.
Malejka, D; Kasprzak, K; Radola, P.
Patol Pol ; 17(4): 511-5, 1966.
Article in Polish | MEDLINE | ID: mdl-5977167

Subject(s)
Blood Proteins/metabolism , Fluorenes , Neoplasms, Experimental , Sulfonamides , Thiazoles , Animals , Carcinoma 256, Walker , Female , Humans , Male , Protein Binding , Rats
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