[Differential diagnosis of congenital fibrosis of the liver and hepatoportal sclerosis]. / Differentsial'no-diagnosticheskie kriterii vrozhdennogo fibroza pecheni i gepatoportal'nogo skleroza.

The article deals with differential-diagnostic criteria of inborn liver fibrosis and hepatoportal sclerosis. Congenital liver fibrosis is inherited and manifests at young age. It is characterized by marked hepatomegaly with stony dense liver, moderate splenomegaly with hypersplenism and portal hypertension in high activity of alkaline phosphatase and 5-HT, renal affection. Fibrosis locates around the biliary ducts. Hepatoportal sclerosis manifests more frequently in the adults with moderate hepatomegaly, marked splenomegaly with hypersplenism and predominance of anemia, high portal hypertension. Fibrosis is moderate and locates around portal vein branches in which thrombi are found.

[Hepatoportal sclerosis--special variant of liver cirrhosis]. / Gepatoportal'nyi skleroz--osobyi variant fibroza pecheni.

The clinical, functional, x-ray and morphological manifestations of hepatoportal sclerosis have been studied. It is assumed that involvement of the intrahepatic branches of the portal vein of the diffuse fibrosis type underlies hepatoportal sclerosis, a condition of unestablished etiology. Differential diagnosis should be made with the portal-hypertension pattern of congenital liver fibrosis and, according to the clinical manifestations, with liver cirrhosis.