ABSTRACT
Remote technology provides an opportunity to extend the reach of clinical care and research for pediatric rare disease. This pilot study evaluated the feasibility and reliability of neuropsychological evaluation, using remote audiovisual technology, in the assessment of children with juvenile Batten disease. Three children with Batten disease and 1 healthy sibling completed a standardized cognitive assessment. Results indicated high agreement between an in-person and a remote evaluator when comparing the subjects' cognitive test scores. This initial test of remote cognitive assessment suggests it is feasible and reliable in children with pediatric neurodegenerative disease, for whom disease burden may limit travel and access to expert care and/or clinical trials.
Subject(s)
Cognition , Neuronal Ceroid-Lipofuscinoses/diagnosis , Neuronal Ceroid-Lipofuscinoses/psychology , Neuropsychological Tests , Telemedicine/methods , Adolescent , Child , Feasibility Studies , Humans , Male , Membrane Glycoproteins/genetics , Molecular Chaperones/genetics , Neuronal Ceroid-Lipofuscinoses/genetics , Pilot Projects , Reproducibility of Results , TravelABSTRACT
Using a multimeasure longitudinal research design, we measured psychopathy with the Youth Psychopathic Traits Inventory (YPI) and the Psychopathy Checklist-Youth Version (PCL-YV) among 122 offending girls. We examined the psychometric properties of the YPI, investigated the association between the YPI and the PCL-YV, and assessed their concurrent and longitudinal association with externalizing problems on the Youth/Adult Self-Report and violent and delinquent behaviors on the Self-Report of Offending. Alphas for the YPI were adequate and there were small to moderate correlations between the YPI and PCL-YV, suggesting that each assesses distinctive personality features. The YPI and the PCL-YV were approximately equivalent in their association with concurrent and longitudinal outcomes with two exceptions, where the YPI demonstrated a stronger association with antisocial behavior. Concurrently, there was a divergent relationship between the psychopathy factor scores and antisocial outcomes. Within 2 years, the psychopathy affective factor, which constrained the YPI and PCL-YV to be equivalent, was associated with externalizing behaviors and the YPI affective factor was associated with violent offending. Approximately 4½ years later, neither measure was significantly related to antisocial behavior after accounting for past behavior. Reasons for continuity and discontinuity in risk identification are discussed.
Subject(s)
Antisocial Personality Disorder/psychology , Personality Inventory , Psychometrics , Adolescent , Antisocial Personality Disorder/diagnosis , Female , Humans , Juvenile Delinquency/psychology , Young AdultABSTRACT
We tested for gender moderation within a multidomain model of antisocial behavior (ASB) among community youth, drawn from the Project on Human Development in Chicago Neighborhoods study. Youths (N = 1,639) were 9 to 12 years old at baseline and were followed for two additional waves, spaced approximately 2.5 years apart. We hypothesized that harsh and physically coercive parenting, a familial level risk factor, would impact individual level risk factors for ASB, such as childhood temperament ratings of emotionality and inhibitory control, and preadolescent externalizing and internalizing symptoms, as well as involvement with antisocial peers. We further hypothesized that this process and its impact on ASB would be moderated by gender. We used both multiple indicator multiple causes and multiple group analyses to test for gender moderation and a structural equation modeling multiple mediation framework to evaluate the strength of indirect effects. We tested the role of family, individual, and peer level influences on ASB, after accounting for the role of known contextual factors, including poverty, race, and neighborhood. Our overall model fit the data well for males and females, indicating harsh parenting, disinhibition, emotionality, and peers exert a strong influence on risk for ASB. Gender moderated the pathway from harsh parenting to externalizing behavior, such that this was a significant pathway for girls, but not boys. We discussed the importance of these findings with regard to intervention planning for youth at risk for ASB and future gender-informed models of ASB.
