Incorporation of cooked barley residue and spent grapes in the ration of pregnant Large White Yorkshire sows and their piglets.

In Kerala and other South Indian States, the ayurvedic by-products are widely available which can adequately be incorporated into pig diets. The objective of this study was to determine the effect of dietary incorporation of cooked barley residue and spent grapes on feed intake, growth performance, and nutrient utilization in sows and their piglets. Using completely randomized design (CRD), fifteen (15) Large White Yorkshire (LWY) pregnant sows with an average body weight of 180.53 kg, 3 weeks before the estimated date of farrowing, were randomly allotted to one of three treatment groups. The dietary treatment groups consisted of T1 (control), fed with a ration containing maize and soya bean meal of 18% CP and 3265 kcal/kg ME, T2 with a ration containing cooked barley residue replacing 25% maize in control, and T3 with a ration containing spent grapes replacing 25% maize in control ration. Data on average daily feed intake (ADFI), fortnightly bodyweight of sows and their piglets were recorded for 63 days. Also, the average daily gain (ADG), feed conversion ratio (FCR), and cost of feed per kg of weight gain of the piglets were calculated. The result showed no significant (P > 0.05) dietary treatment effects on average weekly dry matter intake and fortnightly average body weight gain among the sows in all the three groups. Piglets showed no significant difference (P > 0.05) in total dry matter intake (DMI), total body weight gain, ADG, and FCR among the three groups during the entire study period. No variations were observed for the apparent digestibility of nitrogen-free extract and the availability of magnesium in the three rations. The cost of feed per kg weight gain was lower in piglets belonging to T2 and T3 than the control (T1), though not significant statistically (P > 0.05). It is, therefore, concluded that cooked barley residue and spent grapes could be included up to 25% in the ration of sow and their piglets by partially replacing maize without affecting their overall performances.

Needle stick injuries: a comparison of practice and attitudes in two UK District General Hospitals.

Hospital staff are at risk from occupational exposure to blood-borne viruses due to needle stick injuries. Occupational health departments have invested considerable resources in the prevention of these injuries, which can be very distressing to the affected individuals. We surveyed health care workers, i.e. doctors, nurses and operating department practitioners, in the operating theatre and critical care units of two UK hospitals located in the Midlands and Merseyside to compare attitudes and experiences. There were significant deficiencies in several aspects of the safe practice of universal precautions. These deficiencies were similar in the two hospitals surveyed and may reflect a national trend. We conclude that every individual, department and trust needs to reflect on their practice and address these deficiencies.

Efficacy and safety of 1% rimexolone versus 1% prednisolone acetate in the treatment of anterior uveitis--a randomized triple masked study.

PURPOSE: To evaluate the efficacy and safety of 1% rimexolone versus 1% prednisolone acetate ophthalmic suspension in the treatment of anterior uveitis. METHODS: A randomised triple masked, parallel comparison of rimexolone and prednisolone acetate ophthalmic suspensions was carried out on 78 patients with acute, chronic and recurrent anterior uveitis. Treatment regimen included instillation of one or two drops of drug one hourly through the waking hours during the first week, two hourly in the second week, four times a day in the third week, two times a day for the first 4 days and once a day for the 3 days in the last week. The patient was clinically evaluated on the 3-4th, 7-10th, 14th, 21st and 28th days. The patient was also reviewed on the 30th day. Anterior chamber cells and flare reactions were compared for evaluating the efficacy of the drugs. RESULT: Rimexolone is as effective as prednisolone acetate ophthalmic suspension in the treatment of anterior uveitis. The largest difference found was 0.1 in the flare reaction (statistically insignificant; p = 0.3) and 0.2 score units (statistically significant; p = 0.01) in the cells. Overall, comparison of the drugs shows no clinical significance in the treatment of anterior uveitis by either drug. Difference in intraocular pressure (IOP) was also statistically insignificant (p > 0.05). However, three patients in the prednisolone acetate group and 1 patient from the rimexolone group showed a rise in IOP. CONCLUSION: Rimexolone 1% ophthalmic suspension is as effective as and safer than prednisolone acetate 1% ophthalmic suspension in the treatment of anterior uveitis.

A study of epidural pressures in infants.

BACKGROUND: The pressures exerted on fragile structures in the infant during epidural injections have never been studied previously. METHODS: We measured the pressure changes in the epidural space of 20 infants during injection of local anaesthetic solutions. The pressures developed during passage of the epidural needle through the ligaments of spine and in the epidural space during the injection of 1 ml at two rates of injection, over 1 and 2 min and the residual pressure 1 and 2 min after each injection were studied. RESULTS: The mean pressure while the needle was being advanced through the ligamentum flavum was 69.14 +/- 36.95 mmHg. The epidural pressure after needle had just penetrated the ligament without eliciting the loss of resistance was 1 +/- 9.759 mmHg. A distinct pulsatile waveform identical to the pulse waveform was observed as soon as the epidural space was entered. The pressure rise varied according to the rate of injection. The pressures were 27.79 mmHg when the rate of injection was 1 ml.min(-1), with a residual pressure after 1 min of 12 +/- 5.53 mmHg and 10.14 +/- 5.53 mmHg after 2 min of injection. When the rate of injection was 1 ml.2 min(-1), the pressures were 15.66 +/- 9.48 mmHg with a residual pressure after 1 min of 14.79 +/- 5.15 mmHg and 12.93 +/- 5.46 mmHg after 2 min of injection. CONCLUSIONS: The residual pressures seem to vary more with the volume injected than the rate of injection or the pressures developed during the injection. The relationship between the rate of injection and pressures is significant when compared with adults where the pressures have been measured after an injection rate of 1 ml.s(-1) and 1 ml.5 s(-1). This is a very fast rate compared with our rates of injection of 1 ml over 1 and 2 min. Based on the findings of this study, we recommend a rate of 1 ml.2 min(-1) in infants. In neonates, a slower rate of injection would be preferable.

Continuous axillary block for upper limb surgery in a patient with epidermolysis bullosa simplex.

We report the use of continuous regional block with light general anaesthesia in epidermolysis bullosa simplex. A 4-year-old girl suffering from florid epidermolysis bullosa simplex was scheduled for external fixator (JESS) for manus valgus deformity of the left forearm. Haemoglobin was 7.6 g.dl(-1) and blood chemistry was normal. She had no history of oral bullae, although a younger sibling had died of Bart syndrome with oral lesions. She was sedated with nasal midazolam 0.5 mg.kg(-1). All pressure points were cushioned. Inhalational anaesthesia was given by holding a mask above her face. Only oximetry and capnography were monitored. ECG and noninvasive blood pressure monitoring were avoided. The intravenous cannula was fixed by sutures. An epidural catheter of 0.63 mm OD (21-G) was passed into the axilla for continuous axillary block. Intra- and postoperative course was uneventful with slight bullae at the i.v. site and at the fixator which healed without further damage. The axilla remained free of problems. Continuous peripheral plexus or nerve blocks can be an option in these difficult patients, and can minimize the amount of general anaesthesia along with problems of airway handling and potential subsequent mucosal lesions. The postoperative period was pain free and comfortable.

Continuous caudal epidural analgesia for congenital lobar emphysema: a report of three cases.

IMPLICATIONS: In congenital lobar emphysema, positive pressure ventilation can expand the emphysematous lobe, compressing the normal lung during anesthesia induction. We managed the dual challenges of safe induction and analgesia for thoracotomy by placing thoracic epidural catheters via the caudal insertion site and retaining spontaneous ventilation until thoracotomy.

Intermediate uveitis of pars planitis type in identical twins. Report of a case.

The occurrence of intermediate uveitis in monozygotic twins has rarely been reported in literature. We report the occurrence of this disease condition in identical twins. Twin sisters presented with typical features of intermediate uveitis, which appeared three years earlier in one of the sisters. They were treated with posterior subtenon injection of triamcinolone acetonide and recovered well. Systemic evaluation and laboratory investigations did not reveal any etiology. Cytogenetic high-resolution analysis did not reveal any chromosomal abnormalities. Pedigree analysis revealed no specific transmission pattern. No other family members in three generations had similar ocular disease. Our report indicates that a detailed family history should be taken in intermediate uveitis and examination of other siblings of patients with intermediate uveitis should be performed.