Subject(s)
Asthma/therapy , Chronotherapy , Hypoxia , Adult , Asthma/physiopathology , Humans , Middle Aged , Respiratory Function TestsABSTRACT
Melaxen treatment of bronchial asthma (BA) patients produced positive effects on biorhythms of external respiration. Quantitative characteristics of volume and speed rhythms change insignificantly. The basic quantitative effect consists in internal and external synchronization and elimination of ultradian rhythms indicating stabilization in the system of control and coordination of time structure of external respiration system.
Subject(s)
Asthma/drug therapy , Asthma/physiopathology , Circadian Rhythm/drug effects , Melatonin/analogs & derivatives , Melatonin/pharmacology , Respiration/drug effects , Adult , Female , Forced Expiratory Volume/drug effects , Humans , Male , Melatonin/therapeutic use , Respiratory Function Tests , Vital Capacity/drug effectsABSTRACT
The hypoxic resistance of rats was found to change depending on the period of adaptation and different regimens of cerebral ischemia. The tonus and responsiveness of vegetative nervous system were found to increase in sympathetic nervous system and to decrease in parasympathetic one. Various parameters of cerebral blood flow in high altitude conditions were also studied in cats and humans.
Subject(s)
Adaptation, Physiological/physiology , Altitude , Blood Circulation/physiology , Physical Exertion/physiology , Adaptation, Physiological/drug effects , Adolescent , Adult , Animals , Blood Circulation/drug effects , Cats , Hemodynamics/drug effects , Hemodynamics/physiology , Humans , Hypoxia/physiopathology , Kyrgyzstan , Male , Periodicity , Phenylephrine/pharmacology , Physical Exertion/drug effects , Rats , Time FactorsABSTRACT
Using the Minnesota Code, we analysed ECGs of 58 subjects with smooth adaptation to high altitude (3.600 m) and of 70 patients with acute mountain sickness. In both groups, the 30-day sojourn at high altitude was characterized by ECG signs of the right heart overload; these signs were more marked in patients with acute mountain sickness. It was demonstrated that baseline ECGs (recorded before the ascent) of subjects predisposed to the development of acute mountain sickness showed a higher incidence of right-ventricular hypertrophy, right-atrial hypertrophy, and tachycardia. These ECG features can be used in the prognosis of acute mountain sickness.