ABSTRACT
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Subject(s)
Humans , Retinitis Pigmentosa/diagnostic imaging , Tomography, Optical Coherence , Fundus OculiABSTRACT
Presentamos un caso de una paciente de 3 años de edad con diagnóstico de retinoblastoma en el ojo izquierdo. El curso de la enfermedad obligó a la enucleación de dicho ojo e implantación de una prótesis. Dos años tras la cirugía, se produjo una extrusión parcial de la prótesis en la cavidad anoftálmica y se decidió emplear un sustituto semisintético de duramadre para cubrir el defecto. El uso de un sustituto semisintético de duramadre en este escenario específico no ha sido comunicado previamente
We present a case report of a three-year old patient diagnosed with retinoblastoma in her left eye. The course of the disease made enucleation of the latter eye and a prosthesis implant necessary. Two years after surgery, partial prosthesis extrusion occurred and a semisynthetic dura mater substitute was used as a patch graft to cover the defect. To our knowledge, semisynthetic dura mater substitutes' use in this scenario has not been previously reported
Subject(s)
Humans , Female , Child, Preschool , Anophthalmos/surgery , Dura Mater , Eye Enucleation , Prostheses and Implants , Retinal Neoplasms/surgery , Retinoblastoma/surgeryABSTRACT
We present a case report of a three-year old patient diagnosed with retinoblastoma in her left eye. The course of the disease made enucleation of the latter eye and a prosthesis implant necessary. Two years after surgery, partial prosthesis extrusion occurred and a semisynthetic dura mater substitute was used as a patch graft to cover the defect. To our knowledge, semisynthetic dura mater substitutes' use in this scenario has not been previously reported.
Subject(s)
Anophthalmos/surgery , Dura Mater , Eye Enucleation , Prostheses and Implants , Retinal Neoplasms/surgery , Retinoblastoma/surgery , Child, Preschool , Female , HumansABSTRACT
Un varón de 55 años acudió a nuestro centro con una queratitis infecciosa en el ojo izquierdo afectando a una de las incisiones de una queratotomía radial que se había realizado 34 años antes. La colocación de dos puntos sueltos en dicha incisión fue clave para la resolución de la infección. Este paciente también fue diagnosticado de síndrome del párpado flácido. ¿Puede esto actuar como factor de riesgo para la queratitis infecciosa en pacientes que se han realizado una queratotomía radial? La asociación entre ambas entidades no ha sido descrita con anterioridad y además este caso representa el segundo en el que se describe el uso de puntos sueltos como tratamiento coadyuvante en este tipo de casuística
A 55-year-old male presented with an infectious keratitis in his left eye, affecting one of the incisions of the radial keratotomy he had undergone thirty-four years ago. Suturing the incision with two simple interrupted stitches was key to the resolution of the infection. Floppy eyelid syndrome was also found in this patient. Could this act as a risk factor for infectious keratitis in radial keratotomy? To our knowledge, this is the first reported case describing the association between both conditions, and the second reported case where sutures have been used as an adjuvant treatment in these types of cases
Subject(s)
Humans , Animals , Male , Middle Aged , Blepharoptosis/complications , Keratoconjunctivitis, Infectious/etiology , Keratotomy, Radial/adverse effects , Staphylococcal Infections/etiology , Staphylococcus epidermidis/isolation & purification , Surgical Wound Infection/etiology , Suture Techniques , Keratoconjunctivitis, Infectious/surgery , Staphylococcal Infections/drug therapy , Staphylococcal Infections/surgery , Surgical Wound Infection/drug therapy , Surgical Wound Infection/surgery , Time Factors , Anti-Bacterial Agents/therapeutic use , Debridement , Drug Therapy, Combination , Keratoconjunctivitis, Infectious/drug therapy , Uveitis, Anterior/drug therapy , Uveitis, Anterior/etiology , Uveitis, Anterior/surgeryABSTRACT
A 55-year-old male presented with an infectious keratitis in his left eye, affecting one of the incisions of the radial keratotomy he had undergone thirty-four years ago. Suturing the incision with two simple interrupted stitches was key to the resolution of the infection. Floppy eyelid syndrome was also found in this patient. Could this act as a risk factor for infectious keratitis in radial keratotomy? To our knowledge, this is the first reported case describing the association between both conditions, and the second reported case where sutures have been used as an adjuvant treatment in these types of cases.
Subject(s)
Blepharoptosis/complications , Keratoconjunctivitis, Infectious/etiology , Keratotomy, Radial/adverse effects , Staphylococcal Infections/etiology , Staphylococcus epidermidis/isolation & purification , Surgical Wound Infection/etiology , Suture Techniques , Animals , Anti-Bacterial Agents/therapeutic use , Debridement , Drug Therapy, Combination , Humans , Keratoconjunctivitis, Infectious/drug therapy , Keratoconjunctivitis, Infectious/surgery , Male , Middle Aged , Staphylococcal Infections/drug therapy , Staphylococcal Infections/surgery , Surgical Wound Infection/drug therapy , Surgical Wound Infection/surgery , Time Factors , Uveitis, Anterior/drug therapy , Uveitis, Anterior/etiology , Uveitis, Anterior/surgeryABSTRACT
El dupilumab es un fármaco de reciente aprobación por la Food and Drug Administration (FDA) y la European Medical Agency (EMA) para el tratamiento de la dermatitis atópica moderada-severa en adultos. El incremento de la frecuencia de conjuntivitis asociadas a dupilumab ha sido expuesto en publicaciones y ensayos recientes. Presentamos 2 casos de conjuntivitis corticodependiente tratados satisfactoriamente con ciclosporina al 0,1% (Ikervis(R)). No hay casos previos descritos de conjuntivitis asociada a dupilumab tratados con ciclosporina al 0,1% (Ikervis(R))
Dupilumab is a drug that has recently been approved by the Food and Drug Administration (FDA) and European Medical Agency (EMA) for the treatment of moderate-to-severe atopic dermatitis in adults. An increase in frequency of conjunctivitis related to dupilumab treatment has been reported in recent publications and clinical trials. We report two steroid-dependent cases satisfactorily treated with cyclosporine 0.1% (Ikervis(R)). To our knowledge there are no reported cases of dupilumab-associated conjunctivitis treated with cyclosporine 0.1% (Ikervis(R)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Antibodies, Monoclonal, Humanized/adverse effects , Conjunctivitis/chemically induced , Conjunctivitis/drug therapy , Cyclosporine/therapeutic use , Dermatitis, Atopic/drug therapy , Immunosuppressive Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Conjunctivitis/diagnostic imaging , Fluorometholone/therapeutic use , Glucocorticoids/therapeutic use , Interleukin-4 Receptor alpha Subunit , RecurrenceABSTRACT
Dupilumab is a drug that has recently been approved by the Food and Drug Administration (FDA) and European Medical Agency (EMA) for the treatment of moderate-to-severe atopic dermatitis in adults. An increase in frequency of conjunctivitis related to dupilumab treatment has been reported in recent publications and clinical trials. We report two steroid-dependent cases satisfactorily treated with cyclosporine 0.1% (Ikervis®). To our knowledge there are no reported cases of dupilumab-associated conjunctivitis treated with cyclosporine 0.1% (Ikervis®).
Subject(s)
Antibodies, Monoclonal, Humanized/adverse effects , Conjunctivitis/chemically induced , Conjunctivitis/drug therapy , Cyclosporine/therapeutic use , Dermatitis, Atopic/drug therapy , Immunosuppressive Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Adult , Conjunctivitis/diagnostic imaging , Female , Fluorometholone/therapeutic use , Glucocorticoids/therapeutic use , Humans , Interleukin-4 Receptor alpha Subunit , Male , Middle Aged , RecurrenceABSTRACT
Un varón caucásico de 44 años con antecedentes de psoriasis en placa en tratamiento actualmente con ustekinumab se presentó con una pérdida brusca de visión en su ojo izquierdo. El examen de fondo de ojo mostró una oclusión de la vena central de la retina que coexistía con una oclusión de la arteria central de la retina. Estudios posteriores revelaron una leve policitemia, siendo la causa subyacente desconocida
A 44 year-old Caucasian male with a history of plaque psoriasis currently being treated with ustekinumab presented with sudden loss of vision in his left eye. Fundus examination showed central retinal vein occlusion coexisting with central retinal artery occlusion. Posterior examination revealed mild polycythemia, being the underlying cause unknown
Subject(s)
Humans , Male , Adult , Psoriasis/complications , Retinal Artery Occlusion/etiology , Retinal Vein Occlusion/etiology , Dermatologic Agents/therapeutic use , Psoriasis/drug therapy , Ustekinumab/therapeutic useABSTRACT
Una paciente caucásica de 17 años de edad acudió a nuestro servicio con disminución de la visión; no asociaba otros síntomas en aquel momento. La exploración oftalmológica reveló hallazgos típicos de coroidopatía hipertensiva: manchas de Elschnig y estrías de Siegrist. El examen médico posterior reveló una tensión arterial de 220/155 mm Hg y se determinó que la causa subyacente de dicho trastorno era un carcinoma adrenal metastásico secretor. Este caso representa el primero descrito en el que se asocia la coroidopatía hipertensiva al carcinoma adrenal
A 17 year-old Caucasian female presented with decreased vision, with no other symptoms reported at that time. Ophthalmological examination revealed typical signs of hypertensive choroidopathy, Elschnig spots, and Siegrist streaks. Further medical examination found high blood pressure (220/155 mmHg), with a metastatic hormone-secreting adrenal carcinoma being the underlying cause of these alterations. To our knowledge, this is the first reported case of hypertensive choroidopathy associated with adrenal carcinoma
Subject(s)
Humans , Female , Adolescent , Hypertensive Retinopathy/diagnostic imaging , Hypertensive Retinopathy/etiology , Choroid Diseases/etiology , Choroid Diseases/diagnostic imaging , Adrenal Cortex Neoplasms/complications , Adrenocortical Carcinoma/complications , Tomography, X-Ray Computed , Fluorescein Angiography , Fatal OutcomeABSTRACT
A 17 year-old Caucasian female presented with decreased vision, with no other symptoms reported at that time. Ophthalmological examination revealed typical signs of hypertensive choroidopathy, Elschnig spots, and Siegrist streaks. Further medical examination found high blood pressure (220/155mmHg), with a metastatic hormone-secreting adrenal carcinoma being the underlying cause of these alterations. To our knowledge, this is the first reported case of hypertensive choroidopathy associated with adrenal carcinoma.
Subject(s)
Adrenal Gland Neoplasms/complications , Carcinoma/complications , Choroid Diseases/etiology , Hypertension/complications , Adolescent , Adrenal Gland Neoplasms/metabolism , Carcinoma/metabolism , Choroid Diseases/diagnostic imaging , Fatal Outcome , Female , Humans , Papilledema/diagnostic imaging , Papilledema/etiologyABSTRACT
A 44 year-old Caucasian male with a history of plaque psoriasis currently being treated with ustekinumab presented with sudden loss of vision in his left eye. Fundus examination showed central retinal vein occlusion coexisting with central retinal artery occlusion. Posterior examination revealed mild polycythemia, being the underlying cause unknown.