ABSTRACT
OBJECTIVES: To determine if the Patient-Reported Outcome Measurement Information System (PROMIS) physical function, pain interference, self-efficacy, and global rating of normal function (GRNF) scales are able to accurately characterize a patient's acceptable symptom state (PASS). DESIGN: A cross-sectional analysis, using receiver operator curves and chi-square analysis to explore criteria to determine thresholds (80% and 95% sensitivity/specificity) for PASS that are applicable to PROMIS and GRNF scales. SETTING: Phone survey after primary care. PARTICIPANTS: Patients (N=94) attending primary care for musculoskeletal problems. INTERVENTIONS: Not applicable. MAIN OUTCOMES MEASURES: Accuracy and proportion of patients classified as PASS Yes or No. RESULTS: Receiver operator curve analysis showed significant area under the curve (AUC) values for each PROMIS scale (AUC>.72) and the GRNF rating (AUC=.74). Identified PROMIS thresholds suggested PASS was achieved when scores were at or slightly worse than the US population average. A score of ≥7 and ≤4 characterized patients that were PASS Yes and No, respectively, on the GRNF rating. A moderate (80%) specificity/sensitivity criteria yielded 72.3%-73.5% accuracy for a majority of participants (>69.9%). CONCLUSION: This analysis suggests the PROMIS and GRNF scales are able to characterize PASS status with moderate accuracy (â¼70%) for a large portion of patients (â¼70%). New to this study is the association of self-efficacy with PASS status. PROMIS scales at or slightly worse than the US population average characterized PASS status.