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1.
Malays Fam Physician ; 15(1): 58-60, 2020.
Article in English | MEDLINE | ID: mdl-32284808

ABSTRACT

Obsessive-compulsive disorder (OCD) is a common anxiety disorder which can be chronic and sustained. An OCD sufferer experiences intrusive and repetitive thoughts, impulses, and behaviors, which ultimately cause extreme discomfort. We report a case of a patient that primarily presented with lower urinary tract symptoms who was subsequently treated with antibiotics. Nonetheless, the symptoms persisted. In subsequent consultations, the patient clarified the compulsive nature of his symptoms and was treated as a case of OCD. Therefore, it is crucial for physicians to correctly identify the nature of the symptoms to manage the disorder properly and to avoid unnecessary consultation and treatment. To the best of our knowledge, this is the first report of other presentations of OCD.

2.
J Forensic Odontostomatol ; 37(1): 63-65, 2019 May 01.
Article in English | MEDLINE | ID: mdl-31187744

ABSTRACT

Dental information is one of the three scientific methods of identifying a deceased person. However, when an investigator is faced with dental ante-mortem information that indicates the deceased has had all his teeth extracted, it may be assumed that the dental information will not be useful, especially if no retained roots are visible in the post-mortem triage. The following case report highlights that careful examination including radiography, may reveal specific detailed information which was useful for identification to be established. Two small radiopaque objects were located in the apical area where the upper left canine root apex would have been. The radiopacities size, location, positioning to both each other and to the left maxillary sinus corresponded to ante-mortem radiographs. This case reveals an unusual use of extruded root canal material being of evidential value even though the tooth was extracted.


Subject(s)
Cuspid/diagnostic imaging , Forensic Dentistry/methods , Root Canal Filling Materials , Root Canal Obturation , Tooth Apex/diagnostic imaging , Adult , Humans , Male , Postmortem Changes , Radiography, Panoramic
3.
Cardiol Young ; 23(2): 197-202, 2013 Apr.
Article in English | MEDLINE | ID: mdl-22640635

ABSTRACT

OBJECTIVE: To determine the feasibility and safety of the Conquest Pro wire as an alternative to radiofrequency wire for perforation of atretic pulmonary valve and subsequent balloon dilatation and patent ductus arteriosus stenting in patients with pulmonary atresia with intact ventricular septum. BACKGROUND: Radiofrequency valvotomy and balloon dilatation has become the standard of care for pulmonary atresia with intact ventricular septum in many institutions today. METHODS: We report eight consecutive patients in whom we used the Conquest Pro coronary guidewire, a stiff wire normally reserved for revascularisation of coronary lesions with chronic total occlusion, for perforation of atretic pulmonary valve and subsequent balloon dilatation, and stenting of the patent ductus arteriosus. RESULTS: Perforation of atretic pulmonary valve was successful in seven out of eight cases. Radiofrequency valvotomy was employed after failure of perforation by the Conquest Pro wire in one case where the right ventricular outflow tract was broad based and tapered towards the pulmonary valve, and was heavily trabeculated. Failure of the Conquest Pro wire to perforate the pulmonary valve plate was mainly attributed by the failure to engage the wire at the correct position. CONCLUSION: The Conquest Pro wire for perforation and subsequent interventions in the more straightforward cases of pulmonary atresia with intact ventricular septum is effective and safe, simplifying the entire procedure. However, the radiofrequency generator and wires remain essential tools in the paediatric interventional catheter laboratory.


Subject(s)
Cardiac Catheterization/instrumentation , Cardiac Catheters , Heart Defects, Congenital/surgery , Pulmonary Atresia/surgery , Pulmonary Valve/surgery , Balloon Valvuloplasty/instrumentation , Balloon Valvuloplasty/methods , Cardiac Catheterization/methods , Cohort Studies , Feasibility Studies , Humans , Infant , Infant, Newborn , Treatment Outcome
4.
Pak J Biol Sci ; 11(22): 2560-6, 2008 Nov 15.
Article in English | MEDLINE | ID: mdl-19260333

ABSTRACT

Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. has been conducted. The structure identification was judged based on the spectroscopic data, namely, ultraviolet, MS, one and two-dimensional 1H-NMR and 13C-NMR methods. The cytotoxic constituent was identified as 1-(tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)-5-methyl pyrimidine-2,4(1H,3H)-dione. This constituent hasn't been isolated from sponges as natural product.


Subject(s)
Cytotoxins/chemistry , Cytotoxins/isolation & purification , Furans/chemistry , Furans/isolation & purification , Porifera/chemistry , Thymine/analogs & derivatives , Animals , Biological Products/chemistry , Biological Products/isolation & purification , Biological Products/pharmacology , Cell Line, Tumor , Cell Proliferation/drug effects , Cytotoxins/pharmacology , Furans/pharmacology , HeLa Cells , Humans , Indonesia , Inhibitory Concentration 50 , Magnetic Resonance Spectroscopy , Mass Spectrometry , Molecular Structure , Pyrimidines/chemistry , Pyrimidines/isolation & purification , Pyrimidines/pharmacology , Solubility , Spectrophotometry, Infrared , Thymine/chemistry , Thymine/isolation & purification , Thymine/pharmacology , Transition Temperature
5.
Singapore Med J ; 49(12): e353-5, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19122933

ABSTRACT

Spontaneous spinal epidural haematoma (SSEH) is rare. No identifiable cause is found in the majority of cases, while anticoagulation accounts for up to 17 percent of cases. Aspirin-associated SSEH, however, has rarely been described in literature. A 62-year-old man on prophylactic aspirin presented with symptoms of acute cord compression due to spinal epidural haematoma that was confirmed on magnetic resonance imaging. An emergency decompression laminectomy was performed ten hours after the onset of his symptoms. No vascular anomaly was detected. Our patient recovered well and regained full motor and sensory function. Aspirin is unlikely to be the direct cause of SSEH but may predispose to it, with the underlying cause being a locus minoris resistentiae, consisting of a network of weakened epidural veins. Early diagnosis and treatment are essential for a successful outcome.


Subject(s)
Anticoagulants/adverse effects , Aspirin/adverse effects , Hematoma, Epidural, Spinal/chemically induced , Emergencies , Hematoma, Epidural, Spinal/surgery , Humans , Male , Middle Aged
6.
Article in English | MEDLINE | ID: mdl-11127331

ABSTRACT

Between September 1998 and May 1999, 265 cases of encephalitis were reported from among those involved in pig rearing. A few cases were also reported among abattoir workers. This raised questions of the risk of transmission among those who handled raw pork. A serosurvey was conducted among pork sellers in Seremban town, which is about 20 km from one of the pig rearing areas which had reported cases of encephalitis. It was found that out of the 28 pork sellers tested, only one tested positive for Nipah virus antibodies and that this pork seller also worked in an abattoir in the same district, removing the urinary bladders from slaughtered pigs. Based on these findings, it was concluded that the risk of transmission of the virus from handling raw pork appeared to be low.


Subject(s)
Encephalitis, Viral/transmission , Meat , Occupational Diseases , Paramyxoviridae Infections/transmission , Paramyxovirinae , Swine , Animals , Cross-Sectional Studies , Disease Outbreaks , Encephalitis, Viral/epidemiology , Female , Humans , Malaysia/epidemiology , Male , Middle Aged , Occupational Diseases/epidemiology , Paramyxoviridae Infections/epidemiology , Risk Factors
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