Monitoring Raman emission through state population in cold atoms confined inside a hollow-core fiber.

We study the spontaneous Raman emission in an ensemble of laser-cooled three-level Λ-type atoms confined inside a hollow-core photonic-bandgap fiber using a novel approach to observe the process. Instead of detecting the emitted light, we measure the number of atoms in the ground state as a function of Raman pump time, which eliminates the need to suppress the pump photons with a high-resolution filter. We describe how this measurement can be used to detect superradiant emission from the atomic ensembles and estimate the number of atoms required to observe Raman superradiance in atomic clouds inside a hollow-core fiber.

Case of steroid-responsive encephalopathy from hypoglycaemia.

Hypoglycaemic encephalopathy is a feared complication in the management of patients with diabetes mellitus. We report on a 73-year-old woman with type 1 diabetes managed with an insulin pump who presented unresponsive after an inappropriate insulin bolus. The patient had minimal improvement in her neurological status over 8 days. After administration of 1 g intravenous methylprednisolone, she had dramatic neurological improvement including successful extubation and discharge from the intensive care unit. Steroid responsive encephalopathy is increasingly recognised in practice and literature. However, to the best of our knowledge, this is the first case of hypoglycaemic encephalopathy that responded to high-dose steroids.

Explaining recurring maser flares in the ISM through large-scale entangled quantum mechanical states.

We apply Dicke's theory of superradiance (introduced in 1954) to the 6.7-GHz methanol and 22-GHz water spectral lines, often detected in molecular clouds as signposts for the early stages of the star formation process. We suggest that superradiance, characterized by burst-like features taking place over a wide range of time scales, may provide a natural explanation for the recent observations of periodic and seemingly alternating methanol and water maser flares in G107.298+5.639. Although these observations would be very difficult to explain within the context of maser theory, we show that these flares may result from simultaneously initiated 6.7-GHz methanol and 22-GHz water superradiant bursts operating on different time scales, thus providing a natural mechanism for their observed durations and time ordering. The evidence of superradiance in this source further suggests the existence of entangled quantum mechanical states, involving a very large number of molecules, over distances of up to a few kilometers in the interstellar medium.

Methodology of isfahan tobacco use prevention program: first phase.

Background. Tobacco use continues to be the leading global cause of preventable death. The majority of smokers begin using tobacco products at teen ages. The aims of this study were providing a methodology of Isfahan Tobacco Use Prevention Program and investigating the prevalence of tobacco use and its related factors. Method. It was a cross-sectional study among guidance and high school students in Isfahan province. Initiation, social, psychological (depression and self-efficacy), family, and attitudinal and belief factors and school policy toward smoking (cigarettes and water-pipe) were investigated. Saliva qutinin was given from 5% of participants for determination of accuracy of responses. A self-administered anonymous questionnaire was used for gathering all data. Results. Of all 5500 questionnaires distributed, about 5408 completed questionnaires were returned (with response rate of 98.3%). Of all participants, 2702 (50.0%) were girls and 2706 (50.0%) were boys. Respectively, 4811 (89.0%) and 597 (11.0%) were from urban and rural. Of all participants, 2445 (45.2%) were guidance school and 2962 (54.8%) were high school students. Conclusion. This study will provide a unique opportunity to study prevalence of smoking cigarettes and water-pipe (ghelyan) among guidance and high school students in Isfahan province and determine the role of initiation, social, psychological, family, and attitudinal and belief factors and school policy toward smoking.

Is thromboprophylaxis effective in reducing the pulmonary thromboembolism?

BACKGROUND: Deep vein thrombosis (DVT) is a relatively prevalent disease which causes high costs due to the required diagnostic tests, specialized treatments, and hospital admission. In recent decades, implementation of thromboprophylaxis protocols has significantly reduced the incidence of thromboembolism in hospitals. The present study aimed to compare the incidence of venous thromboembolism before and after implementation of the mentioned protocol in hospital with identified risk factors and underlying diseases. METHODS: In this case-control group, 385 patients at the risk of DVT, some before and some after implementation of the protocol were studied. Therefore, the level of thromboprophylaxis and the incidence of venous thromboembolism were compared before and after the protocol. Data was entered into SPSS(15) and analyzed by chi-square and t tests RESULTS: Out of 385 patients, 34 patients (8.8%) had venous thromboembolism while 351 (91.2%) were not affected. The incidence of venous thromboembolism was significantly different before and after the implementation of the protocol (17.7% vs. 5.9%; P < 0.001). The incidence of venous thromboembolism in patients not receiving thromboprophylaxis was almost 5 times higher than those who received it (20.7% vs. 5.1%). The frequency distribution of thromboembolism had a significant difference in the two above mentioned groups (P < 0.001). CONCLUSION: Thromboprophylaxis protocol reduced venous thromboembolism incidence in patients with underlying diseases which increase the risk of the complication.

Association of social support and coping strategies with acute coronary syndrome: a case-control study.

BACKGROUND: Psychological factors have been recently proposed as cardiovascular risk factors. This study was designed to evaluate the association of lifelong coping strategies and social support with progression of chronic stable angina (CSA) to acute coronary syndrome (ACS). METHODS AND MATERIALS: Coping strategies and social support of patients based on a stress management questionnaire and Norback social support questionnaire were evaluated in a case-control study. Seventy eight hospitalized patients with ACS and 146 patients with CSA were included as the case and control groups, respectively. Positive angiographic findings were defined as the criteria for CSA. Logistic regression analysis was used to examine the aforementioned association. RESULTS: The mean age of 224 participants was 55±10.4 years and 69.6% of them were male. After adjusting for age, sex, and traditional coronary artery disease risk factors, acute life event [odds ratio (OR): 1.09, 1.05-1.13 95%CI], maladaptive coping strategies (OR: 5.81, 1.93-17.49 95%CI), adaptive coping strategies (OR: 0.21, 0.05-0.94 95%CI), total functional support (OR: 0.49, 0.26-0.97 95%CI), and total network support (OR: 0.27, 0.15-0.53 95%CI) were significantly associated with ACS. CONCLUSION: Improvement in social support and adaptive coping strategies should be considered in patients with chronic ischemic heart disease (IHD) to reduce the risk of ACS.

Relationship between depression and apolipoproteins A and B: a case-control study.

OBJECTIVE: To investigate the relation between major depressive disorder and metabolic risk factors of coronary heart disease. INTRODUCTION: Little evidence is available indicating a relationship between major depressive disorder and metabolic risk factors of coronary heart disease such as lipoprotein and apolipoprotein. METHODS: This case-control study included 153 patients with major depressive disorder who fulfilled the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV), and 147 healthy individuals. All participants completed a demographic questionnaire and Hamilton rating scale for depression. Anthropometric characteristics were recorded. Blood samples were taken and total cholesterol, high-and low-density lipoproteins and apolipoproteins A and B were measured. To analyze the data, t-test, χ² test, Pearson correlation test and linear regression were applied. RESULTS: Depression was a negative predictor of apolipoprotein A (ß = -0.328, p<0.01) and positive predictor of apolipoprotein B (ß = 0.290, p<0.05). Apolipoprotein A was inversely predicted by total cholesterol (ß = -0.269, p<0.05) and positively predicted by high-density lipoprotein (ß = 0.401, p<0.01). Also, low-density lipoprotein was a predictor of apolipoprotein B (ß = 0.340, p<0.01). The severity of depression was correlated with the increment in serum apolipoprotein B levels and the decrement in serum apolipoprotein A level. CONCLUSION: In view of the relationship between apolipoproteins A and B and depression, it would seem that screening of these metabolic risk factors besides psychological interventions is necessary in depressed patients.

Non-alcoholic Steatohepatitis in a Sample of Iranian Adult Population: Age is a Risk Factor.

OBJECTIVES: Non-alcoholic Steatohepatitis (NASH) is a cause of cirrhosis. Detecting its preventable causes could be useful in decreasing the disease and its complications. This study aimed to assess the prevalence of NASH in adult population living in Isfahan city as a sample of Iranian population. METHODS: Blood samples of 2030 individuals referring to Dr. Shariati Hospital for routine health checkup were collected. All individuals with high liver enzymes [aspartate aminotransferase (AST) and/or Alanine aminotransferease (ALT)] were included in the study. Known causes of altered liver enzymes were excluded. Second blood samples were obtained 6 months later and those cases with persistent enzyme elevation were surveyed with ultrasonography. RESULTS: In the first survey, 234 individuals (11.5 %) had ALT levels of more than 40 U/L. By rechecking samples after 6 months, 50% of all high serum ALT individuals remained at high level. After conducting complementary biochemical tests, 3.3% of the population was considered to have NASH; 20% of NASH cases did not have any abnormal findings in ultrasonography. Hypercholesterolemia was the most coexisting risk factor in NASH cases. We found a reverse correlation between ALT level and age (P = 0.02). CONCLUSIONS: The prevalence of NASH was comparable with other countries. According to the significantl correlation between ALT level and age, preventive interactions in younger individuals would decrease the incidence of NASH.

Relationship between depression and apolipoproteins A and B: a case-control study

OBJECTIVE: To investigate the relation between major depressive disorder and metabolic risk factors of coronary heart disease. INTRODUCTION: Little evidence is available indicating a relationship between major depressive disorder and metabolic risk factors of coronary heart disease such as lipoprotein and apolipoprotein. METHODS: This case-control study included 153 patients with major depressive disorder who fulfilled the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV), and 147 healthy individuals. All participants completed a demographic questionnaire and Hamilton rating scale for depression. Anthropometric characteristics were recorded. Blood samples were taken and total cholesterol, high-and low-density lipoproteins and apolipoproteins A and B were measured. To analyze the data, t-test, χ2 test, Pearson correlation test and linear regression were applied. RESULTS: Depression was a negative predictor of apolipoprotein A (β = -0.328, p<0.01) and positive predictor of apolipoprotein B (β = 0.290, p<0.05). Apolipoprotein A was inversely predicted by total cholesterol (β = -0.269, p<0.05) and positively predicted by high-density lipoprotein (β = 0.401, p<0.01). Also, low-density lipoprotein was a predictor of apolipoprotein B (β = 0.340, p<0.01). The severity of depression was correlated with the increment in serum apolipoprotein B levels and the decrement in serum apolipoprotein A level. CONCLUSION: In view of the relationship between apolipoproteins A and B and depression, it would seem that screening of these metabolic risk factors besides psychological interventions is necessary in depressed patients.