ABSTRACT
OBJECTIVE: To describe COVID-19 in children and the differences between the two waves. METHODS: The electronic medical records of children younger than 16 y of age with laboratory-confirmed COVID-19 infection between June 1st 2020 and May 31st 2021 at Christian Medical College, Vellore were retrospectively reviewed. Demographic, clinical, and laboratory data were collected on a predesigned case record form and analyzed. RESULTS: A total of 988 children were diagnosed with confirmed COVID-19 during the study period. Of these, there were 585 children diagnosed during the 1st wave (June 2020-Feb 2021) and 403 children during the 2nd wave (March 2021-May 2021). It was found that loose stools and rash were significantly more frequent during the 1st wave and fever, cough, coryza, heart rate and temperature were significantly more during the 2nd wave. There was no significant difference between the two groups in terms of requirement of oxygen therapy, need for ICU admission, duration of ICU stay or hospital stay, or severity of illness. Mortality was significantly higher during the 2nd wave (0.3% vs. 2%). CONCLUSION: The COVID-19 pandemic among children during the 1st and 2nd waves were similar in severity, though there was a higher mortality during the 2nd wave.
Subject(s)
COVID-19 , Child , Humans , COVID-19/epidemiology , Pandemics , SARS-CoV-2 , Retrospective Studies , Tertiary Care Centers , India/epidemiologyABSTRACT
OBJECTIVE: To study the clinical profile and outcome of adolescent onset anorexia nervosa at a tertiary care center in Southern India. METHOD: Review of hospital records of adolescents diagnosed with anorexia nervosa. Outcome was assessed for those with a follow-up of atleast one year, by outpatient visit or by a telephonic interview. FINDINGS: Data of 43 patients (28% males) with mean (SD) age at presentation of 13.4 (1.7) years were included. The mean (SD) BMI at presentation was 13.8 (3.2) kg/m2, the lowest being 8.3 kg/m2. 33 (76%) patients were hospitalized for nutritional rehabilitation. Of the 15 patients followed up 1-5 years later, one had died and 11 had achieved normal weight for age. CONCLUSIONS: As compared to other studies, this study showed a higher proportion of boys with anorexia nervosa. Further research is necessary to understand factors affecting long-term outcome.
Subject(s)
Anorexia Nervosa , Adolescent , Anorexia Nervosa/diagnosis , Anorexia Nervosa/epidemiology , Female , Humans , India/epidemiology , Male , Tertiary Care CentersSubject(s)
Abnormalities, Multiple/diagnostic imaging , Heart Atria/abnormalities , Heart Defects, Congenital/diagnostic imaging , Stroke/etiology , Vascular Malformations/diagnostic imaging , Vena Cava, Superior/abnormalities , Computed Tomography Angiography/methods , Echocardiography/methods , Female , Follow-Up Studies , Heart Defects, Congenital/complications , Humans , Infant , Infarction, Middle Cerebral Artery/diagnostic imaging , Infarction, Middle Cerebral Artery/etiology , Paresis/etiology , Paresis/physiopathology , Rare Diseases , Risk Assessment , Stroke/diagnostic imaging , Stroke/physiopathology , Vascular Malformations/complicationsABSTRACT
Basidiobolomycosis is an uncommon cutaneous zygomycete infection typically seen in immunocompetent individuals. Diagnosis can be made by biopsy and fungal culture of the lesion. Treatment with Potassium iodide and co-trimoxazole is simple and effective. Early and accurate diagnosis of basidiobolomycosis is essential to avoid dissemination and mortality. We present a case with basidiobolomycosis resembling Fournier's gangrene.
