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J Environ Pathol Toxicol Oncol ; 39(2): 159-177, 2020.
Article in English | MEDLINE | ID: mdl-32749125

ABSTRACT

This review delineates the potential of naturally occurring substances for coronary artery disease (CAD), mainly coronary ischemia and its management, with their active constituents and probable mechanisms of action. As per the WHO, statistical incidence of CAD has increased in several countries. The number of coronary events worldwide has been increasing, and may increase even more in the near future. Meanwhile, increased sedentary behavior and poor diet will encourage the prevalence of CAD worldwide. As far as treatment is concerned, current conventional therapies have limitations due to their increased adverse events. The current approach to the management of CAD has certain lacunas that need to be overcome. Thus, new therapeutic options should be explored using traditional literature and current scientific data on natural products. The present review article deals with current knowledge associated with naturally occurring substances for the management of CAD.


Subject(s)
Biological Products/pharmacology , Coronary Artery Disease/drug therapy , Biological Products/therapeutic use , Coronary Artery Disease/epidemiology , Coronary Artery Disease/physiopathology , Herbal Medicine , Humans
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