ABSTRACT
Six patients with lupus (five with systemic lupus erythematosus and one with discoid lupus) were treated with moderate-dose to high-dose standard radiation treatment for breast cancer (four patients), Hodgkin's disease (one patient), and thymoma (one patient). None of the patients had severe acute or late radiation complications in the skin or subcutaneous tissues treated, with a follow-up of 7-121 months. Systemic lupus erythematosus is not an absolute contraindication to radiotherapy, which can be offered to patients with malignant disease that can be appropriately treated with this modality.
Subject(s)
Breast Neoplasms/radiotherapy , Hodgkin Disease/radiotherapy , Lupus Erythematosus, Discoid/complications , Lupus Erythematosus, Systemic/complications , Thymoma/radiotherapy , Adult , Breast Neoplasms/complications , Contraindications , Female , Hodgkin Disease/complications , Humans , Middle Aged , Radiotherapy , Thymoma/complicationsABSTRACT
Low-grade astrocytomas are the single most common form of pediatric brain tumor, representing 28% of the total. Prolonged survival and even cures can be expected in a substantial proportion of patients who present with these tumors. For a variety of reasons, the overall oncologic management of children with low-grade astrocytomas is extremely controversial. This article analyzes the available information related to the management of various forms of low-grade astrocytoma in childhood while awaiting the performance of a long-term national cooperative study on the natural history and management of this common pediatric brain tumor.
