ABSTRACT
Three teeth were extracted in three sessions in a 15-year-old girl with Glanzmann's thrombasthenia who suffered in the past severe bleeding and required platelet transfusions. The extraction sites were treated locally with autologous fibrin glue in adjunct of tranexamic acid swish and swallow rinses. No systemic platelet infusion was employed as a preventive measure. No postoperative bleeding occurred.
Subject(s)
Dental Care for Chronically Ill/methods , Fibrin Tissue Adhesive/therapeutic use , Thrombasthenia , Tooth Extraction/methods , Adolescent , Female , Humans , Mouthwashes/therapeutic use , Oral Hemorrhage/prevention & control , Tooth Extraction/adverse effects , Tranexamic Acid/therapeutic useABSTRACT
Eighty patients with various bleeding disorders underwent 135 extractions without preventive replacement hematologic therapy. The local hemostatic control involved the use of fibrin glue Beriplast. Secondary bleeding occurred in 9 of 12 patients with severe hemophilia when the concentration of the aprotinin in the fibrin glue was 1,000 KIU/ml. When it was increased to 10,000 KIU/ml and swish and swallow rinses of tranexamic acid before and after the dental extractions were added, only 3 of 25 hemophilia patients suffered from secondary bleeding. Local use of fibrin glue is a safe and cost-effective tool to treat patients with severe bleeding disorders. None of the 43 patients with coagulopathies other than severe hemophilia suffered bleeding after extractions.
Subject(s)
Blood Coagulation Disorders , Blood Loss, Surgical/prevention & control , Dental Care for Disabled , Fibrin Tissue Adhesive/therapeutic use , Tooth Extraction , Adolescent , Adult , Aged , Child , Child, Preschool , Humans , Middle AgedABSTRACT
Dental extraction in patients receiving long-term oral anticoagulant therapy is a controversial issue. Continuation of anticoagulation exposes the patient to serious hemorrhage, whereas cessation of therapy increases the risk of thromboembolism. Forty patients treated by coumarin underwent 63 tooth extractions, without a change in the therapeutic protocol of anticoagulation. The biologic adhesive Beriplast was used successfully to achieve local hemostasis at the site of the surgical wound. Apart from one patient who had mild oozing, there were no incidences of postsurgical hemorrhage.
Subject(s)
Anticoagulants/administration & dosage , Dental Care for Disabled , Fibrin Tissue Adhesive/therapeutic use , Hemostatic Techniques , Oral Hemorrhage/prevention & control , Tooth Extraction , Administration, Oral , Adult , Aged , Coumarins/administration & dosage , Heparin/administration & dosage , Humans , Middle Aged , Thromboembolism/prevention & controlABSTRACT
Due to insensitivity to pain, various complications in familial dysautonomia were reported. To the best of our knowledge, occurrence of Riga-Fede disease was not described. A simple restorative procedure helped to bring about the rapid healing of the ulcerative lesions of Riga-Fede disease.
Subject(s)
Dysautonomia, Familial , Lingual Frenum/pathology , Tongue Diseases/pathology , Ulcer/pathology , Humans , Infant , MaleSubject(s)
Incisor/injuries , Tooth Avulsion/diagnosis , Child, Preschool , Humans , Male , Maxilla , Nasal Cavity/diagnostic imaging , RadiographyABSTRACT
Vitamin D-resistant rickets (familial hypophosphatemia) is a systemic disease secondary to defective renal-tubular reabsorption of phosphate. The major oral manifestations are spontaneous abscesses in a caries-free dentition. Pulpotomies or extractions were frequently described in the dental literature as the therapies of choice. This article presents a new prophylactic approach utilizing zinc oxide--eugenol pulpectomies and full crown coverage in an attempt to retain the primary dentition and prevent abscess formation.
