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1.
Bull Soc Pathol Exot ; 104(2): 125-34, 2011 May.
Article in French | MEDLINE | ID: mdl-21451954

ABSTRACT

A new H1N1 virus originating from swine recently emerged as the first influenza pandemic of the 21st century. On July 3, 2009, this new influenza A(H1N1) virus (S-OIV) of swine origins was identified in Réunion Island, a French overseas department located in the southern hemisphere. The present study describes the characteristics of the epidemic from July 3 to September 30, 2009. Among the 479 patients included in our study (236 males, 37.3 ± 19.0 years), 255 (53.2%) were reported to have comorbidities or risk factors (RF) for complications. Complications occurred in 160 patients (33.4%). The most common complications were bronchial hyperreactivity (52.7%), pneumonia (32.1%), and decompensation caused by comorbidity (17.9%). 111 patients (23.2%) required hospitalization. Patients aged 65 and over, accounted for 11.9% of all patients, 32.4% of hospitalized patients and 22.5% of complicated S-OIV infections. Regardless of age, comorbidity and/or RF were reported in 80.0% of complicated S-OIV infections and 91.0% of hospitalized patients. Recommendations for surveillance, prevention and policy for persons with RF, particularly respiratory disease, are justified. However, the absence of risk factors did not prevent the occurrence of complications, present in 14.3% of the cases.


Subject(s)
Emergency Service, Hospital/statistics & numerical data , Epidemics , Influenza A Virus, H1N1 Subtype , Influenza, Human/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Antiviral Agents/therapeutic use , Bronchial Spasm/etiology , Comorbidity , Female , Hospitalization/statistics & numerical data , Humans , Influenza, Human/complications , Influenza, Human/drug therapy , Influenza, Human/virology , Male , Middle Aged , Oseltamivir/therapeutic use , Reunion/epidemiology , Risk Factors , Time Factors , Young Adult
2.
Parassitologia ; 33(2-3): 219-23, 1991 Dec.
Article in English | MEDLINE | ID: mdl-1844515

ABSTRACT

Data are reported from a malaria survey carried out in June 1991 in the small village of Ankadimbazinba, near Miantso, about 45 km North-West of Antananarivo (Madagascar). The objective was to evaluate the level of transmission of P. falciparum by entomological, parasitological and serological indices. All indices were found consistent with the description of a focus of hyperendemic transmission dependent on the presence of An. funestus at high density, corresponding to more than 50 females per house collected by hand catch. The positivity rate for the circumsporozoite protein (CS) of P. falciparum in blood-fed or gravid An. funestus was 2.0% (11/562) in the house resting sample. The parasite rate in the village population was 47.9% reaching 68.4% in the 0-14 age group and the gametocyte rate in the total sample was 25.0%. The seroprevalence of P. falciparum antisporozoite antibodies was 40.0% in children under 15 years old, 84.2% in the 15-29 age group and 90.9% in the over 29 age group.


Subject(s)
Anopheles/parasitology , Insect Vectors/parasitology , Malaria, Falciparum/epidemiology , Plasmodium falciparum/isolation & purification , Adult , Animals , Cattle , Child , Child, Preschool , Disease Reservoirs , Female , Housing , Housing, Animal , Humans , Infant , Madagascar/epidemiology , Malaria, Falciparum/transmission , Middle Aged , Prevalence , Seroepidemiologic Studies , Swine
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