[Osteogenic sarcoma combined with non-ossifying fibroma in one bone (author's transl)]. / Monostotische Kombination eines osteogenen Sarkoms mit einem nicht-ossifizierenden Knochenfibrom

In a 15 year old girl a combination of osteogenic sarcoma and non-ossifying fibroma in the distal shaft of femur is reported and discussed.

[Determination of monoamine oxidase and catechol-O-methyltransferase in human blood components: methodical aspects (author's transl)]. / Bestimmung der Monoaminoxidase und Catechol-O-methyltransferase in menschlichen Blutbestandteilen: Methodische Aspekte

Controversal findings are reported with respect to alternations in activity of monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) in psychoses. Initially we determined the interindividual differences of some biochemical properties of the two enzymes in normal control subjects. Platelet rich plasma and lysate of red blood cells, respectively, were used for assay. Enzyme activity was referred to mg of protein or mg hemoglobin and number of platelets, respectively. Substrates used for COMT assay were: 3,4-dihydroxybenzaldehyde and 3,4-dihydroxybenzoic acid; for MAO determination: tyramine, tryptamine and phenylethylamine. Interindividual as well as intraindividual differences in the biochemical characteristics (apparent Km, Vmax, IC50, meta/para ratio of O-methylation in vitro) were remarkably low, the coefficient of variation was in the range of 30%.