ABSTRACT
In order to know the etiology of purulent meningitis in infant and children, a retrospective study was done; 709 cases of a pediatric infectious disease service were analyzed. Diagnosis was established either by antigen detection (coagglutination) or bacterial culture. In 334/709 (48%) the bacterial agent was identifies. Haemophilus influenzae type b (70%), Streptococcus pneumoniae (14%), Enterobacteriaceae (8%) and Streptococcus sp (6.5%) were the most frequent. According to our results the epidemiologic pattern of purulent meningitis has not changed. A therapeutic approach is suggested.
Subject(s)
Bacterial Infections/etiology , Meningoencephalitis/etiology , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Bacteria/drug effects , Bacteria/isolation & purification , Bacterial Infections/drug therapy , Bacterial Infections/microbiology , Cerebrospinal Fluid/microbiology , Child , Child, Preschool , Humans , Infant , Meningoencephalitis/drug therapy , Meningoencephalitis/microbiology , Mexico , Microbial Sensitivity TestsABSTRACT
These is presented a study of 50 patients suffering TB and AIDS. The universe was divided in two: group I, when TB was considered the first manifestation of AIDS; (27 males and 2 females). Group II, when TB was preceded by some opportunistic infection, some kind of cancer, or some clinical symptoms compatible with wasting syndrome; (20 males and 1 female). There was no difference between the two groups regarding epidemiology, since homo-bisexuality was the most frequent among males. Neither were significantly different the clinical features of TB in both groups, and the most frequent symptoms were: fever, productive cough and painful lymphadenopathy. Both groups showed miliary infiltration on the lung X-rays; lymph nodes were the most frequent extrapulmonary localization. The only significant difference was found when the mortality was compared group I, 10 patients (34.4%) vs 16 (76%) from group II (p less than 0.01). An other part of the study is related with the efficacy of rifampin and isoniazide (31 cases), compared to their efficiency when these drugs are used combined with a third one (10 cases); the results showed no significant difference.
