ABSTRACT
AIM: The aim of this paper was to evaluate the effect of a treatment with glycophosphopeptide on Olympic high platform divers during training and competition by measuring lymphocytes and cortisol in peripheral blood, and secretory immunoglobin A in saliva (sIgA). METHODS: Two groups of 8 divers were given a 14-day treatment of capsules (Gp or placebo) three times per day. Measurements of the peripheral blood lymphocytes (TCD3+, TCD4+ and T CD8+), plasma cortisol and IgA levels in saliva were made on day 0, 21 and 150. RESULTS: There was no significant difference found between the Gp- and placebo-treated groups regarding the increase in IgA between basal and first, or first and second measurements. The fact that there was a significant increase in S-IgA (9.89 ± 0.44 to 10.59±0.55, P=0.001) and B CD19+ (345.13±108.24 to 484.75±120.54, P=0.025) in the Gp- and not in the placebo-treated group between the basal and first measurement was due to the variation among the athletes of the latter group, and not the increase itself, indicating that Gp acted as an immunomodulator. It was apparently the exercise and not the Gp treatment that caused the increase in S-IgA and B CD19+ at the first and second measurements. CONCLUSION: The current study reports that with athletes who practiced moderately intense exercise, which stimulated the immune response, a Gp treatment of two weeks seems to have acted only as an immunomodulator that reduced the variation in the increased levels of IgA and B CD19+.
Subject(s)
Adjuvants, Immunologic/pharmacology , Diving/physiology , Exercise/physiology , Immunity, Innate/drug effects , Immunoglobulin A, Secretory/metabolism , Saliva/metabolism , T-Lymphocytes/drug effects , Adolescent , Double-Blind Method , Female , Follow-Up Studies , Humans , Lymphocyte Count , Male , Prospective Studies , Respiratory Tract Infections/immunology , Respiratory Tract Infections/metabolism , Respiratory Tract Infections/prevention & controlABSTRACT
Con el objetivo de determinar la capacidad aerobica de los Floretistas cubanos de calidad a traves de una prueba que brinda información para cuando alguna razón no sea posible realizar determinaciones de consumo máximo de oxigeno en el laboratorio se realizó este trabajo. El consumo de oxigeno relativo (ml\kg peso corporal) de 12 deportistas 6 del sexo masculino y 6 sexo femenino fue determinado de forma indirecta a traves del Test de Cooper y tambien 48 horas después realizando una prueba de esfuerzo hasta el agotamiento en una esfera rodante acoplada a un analizador de gases, encontrandose aceptable correlación. El valor promedio de consumo de oxigeno realivo en los Floretistas del sexo masculino y femenino mediante el Test de Cooper fue 51,96 ml\min.kg.pc y 45,13 ml\min.kg.pc respectivamente y el obtenido de forma directa en la esfera fue de 47,55 ml\min.kg.pc y 43,10 ml\kg.pc en atletas hombres y mujeres.(AU)
