Satisfacción de los servicios de medicina alópata vs la medicina tradicional en Oaxaca, México / Satisfaction with Allopathic Medicine Services versus Traditional Medicine in Oaxaca, Mexico

Introducción: Se ha reportado baja satisfacción con la atención recibida en el primer y el segundo nivel de atención de instituciones públicas. Existe incremento del uso de la medicina tradicional. Objetivo: Comparar el nivel de satisfacción percibida por los pacientes que acuden a los servicios de medicina alópata y medicina tradicional. Métodos: Estudio descriptivo, transversal y comparativo. La población estuvo constituida por pacientes que acudieron al Centro de Salud Urbano y curandero de medicina tradicional de la misma comunidad. El tamaño de la muestra fue de 344 personas, seleccionados por muestreo sistemático. Resultados: La media de edad fue de 40,6 años (DE=16,1), predominó el sexo femenino, los casados, con educación primaria y de religión católica. El padecimiento por el cual acudieron a los servicios de medicina alópata fue por consulta familiar y en la medicina tradicional por espanto. Se encontraron diferencias significativas entra la satisfacción medicina tradicional y alópata. Los pacientes reportan mayor satisfacción en los servicios de medicina tradicional. Conclusiones: Los pacientes perciben mayor satisfacción en la explicación, trato y tratamiento médico en la medicina tradicional(AU)

Introduction: Low satisfaction with the care received at the first and second levels in public institutions has been reported. There is an increase in the use of traditional medicine. Objective: To compare the level of satisfaction perceived by patients attending allopathic and traditional medicine services. Methods: Descriptive, cross-sectional and comparative study. The population consisted of patients attending the Urban Health Center and traditional medicine healer in the community of Oaxaca. The sample size was 344 people, selected by systematic sampling. Results: The mean age was 40.6 years (SD=16.1). There was a predominance of the female sex, married persons, with primary education and Catholic religion. The condition for which they sought allopathic medicine services was that they received family advice and, in traditional medicine, for fear. Significant differences were found between satisfaction with traditional and allopathic medicine. Patients report greater satisfaction in traditional medicine services. Conclusions: Patients perceive greater satisfaction in the explanation, treatment and medical treatment in traditional medicine(AU)

Mitochondrial bound hexokinase type I in normal and streptozotocin diabetic rat retina.

Diabetic retinopathy is thought to be trigger by glucose- induced oxidative stress which leads to an increase of the mitochondrial permeability through opening the permeability transition pore (MTP). In several cell types, hexokinases interact with the mitochondria regulating MTP opening, avoiding cytochrome c release. We studied HK I mitochondrial proportion in control and streptozotocin-induced diabetic rat retinas. In the normal retina, 50% of HK I was linked to mitochondria, proportion that did not change up to 60 days of diabetes. Mitochondria from normal and diabetic rat retinas showed a limited swelling, and similar cytochrome c levels. G-6-P and glycogen content increased 3-6-fold in diabetic rat retinas, while lactate content did not vary. Results suggest that mitochondrial bound HK produce G-6-P and drove it to glycogen synthesis, controlling ROS production and lactate toxicity.

Mitochondrial activity in different regions of the brain at the onset of streptozotocin-induced diabetes in rats.

Diabetes affects a variety of tissues including the central nervous system; moreover, some evidence indicates that memory and learning processes are disrupted. Also, oxidative stress triggers alterations in different tissues including the brain. Recent studies indicate mitochondria dysfunction is a pivotal factor for neuron damage. Therefore, we studied mitochondrial activity in three brain regions at early type I-diabetes induction. Isolated mitochondria from normal hippocampus, cortex and cerebellum revealed different rates of oxygen consumption, but similar respiratory controls. Oxygen consumption in basal state 4 significantly increased in the mitochondria from all three brain regions from diabetic rats. No relevant differences were observed in the activity of respiratory complexes, but hippocampal mitochondrial membrane potential was reduced. However, ATP content, mitochondrial cytochrome c, and protein levels of ß-tubulin III, synaptophysin, and glutamine synthase were similar in brain regions from normal and diabetic rats. In addition, no differences in total glutathione levels were observed between normal and diabetic rat brain regions. Our results indicated that different regions of the brain have specific metabolic responses. The changes in mitochondrial activity we observed at early diabetes induction did not appear to cause metabolic alterations, but they might appear at later stages. Longer-term streptozotocin treatment studies must be done to elucidate the impact of hyperglycemia in brain metabolism and the function of specific brain regions.