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J Am Acad Dermatol ; 50(2 Suppl): S1-3, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14726854

ABSTRACT

We describe the third case (to our knowledge) of multiple basal cell carcinoma associated with myotonic dystrophy and carry out a genetic study of the tumor comparing it with healthy skin. We consider that our results show that this association might be not a purely random phenomenon and that the particular genetic characteristics of this disorder might have a role in the pathogenesis of the tumor.


Subject(s)
Carcinoma, Basal Cell/genetics , Mosaicism/genetics , Myotonic Dystrophy/genetics , Neoplasms, Second Primary/genetics , Skin Neoplasms/genetics , Adult , Carcinoma, Basal Cell/complications , Carcinoma, Basal Cell/diagnosis , Diagnosis, Differential , Eyelids , Face , Genetic Counseling , Humans , Male , Myotonic Dystrophy/complications , Neoplasms, Second Primary/complications , Neoplasms, Second Primary/diagnosis , Protein Kinases/genetics , Skin Neoplasms/complications , Skin Neoplasms/diagnosis , Thorax , Trinucleotide Repeat Expansion
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