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1.
Med J Malaysia ; 63(1): 47-50, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18935733

ABSTRACT

In Malaysia, transbronchial needle aspiration (TBNA) is a relatively new procedure performed only in a handful of respiratory centres. We reviewed TBNA of mediastinal lymph node performed in Hospital Tengku Ampuan Afzan (HTAA) to determine the yield and its complications. Data was retrieved from endoscopy databases and patients' records, CT thorax images and all cytological and histological slides were reviewed. Twenty-five patients had TBNA performed. TBNA was positive in 15 patients (60%). Overall, 80% had confirmed malignancy after bronchoscopy. Only four patients had documented bleeding after TBNA and in two of them, bleeding stopped spontaneously and another two patients required diluted adrenaline to stop the bleed. No mortality was reported from this procedure. Hence, TBNA is a safe procedure.


Subject(s)
Biopsy, Needle/methods , Lymph Nodes/pathology , Bronchoscopy , Humans , Lung Neoplasms/pathology , Mediastinum
2.
Med J Malaysia ; 63(2): 178-81, 2008 Jun.
Article in English | MEDLINE | ID: mdl-18942315

ABSTRACT

In Malaysia, transbronchial needle aspiration (TBNA) is a relatively new procedure performed only in a handful of respiratory centres. We reviewed TBNA of mediastinal lymph node performed in Hospital Tengku Ampuan Afzan (HTAA) to determine the yield and its complications. Data was retrieved from endoscopy databases and patients' records, CT thorax images and all cytological and histological slides were reviewed. Twenty-five patients had TBNA performed. TBNA was positive in 15 patients (60%). Overall, 80% had confirmed malignancy after bronchoscopy. Only four patients had documented bleeding after TBNA and in two of them, bleeding stopped spontaneously and another two patients required diluted adrenaline to stop the bleed. No mortality was reported from this procedure. Hence, TBNA is a safe procedure.


Subject(s)
Biopsy, Fine-Needle/methods , Adult , Aged , Bronchi , Female , Humans , Lung Neoplasms/diagnosis , Male , Middle Aged
3.
Malays J Pathol ; 30(2): 129-32, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19291924

ABSTRACT

Pulmonary cryptococcosis can be clinically silent in non-HIV infected patients but can also present as nodules and masses on the chest radiograph, which can be mistaken for tuberculosis or lung cancer. Common symptoms include fever and cough, and uncommonly haemoptysis. This report illustrates a non-HIV infected patient whose main complaint was haemoptysis and headache. He was diagnosed with pulmonary cryptococcosis from biopsy of an endobronchial mass found on flexible bronchoscopy. Disseminated cryptoccoccal infection should be considered as a differential diagnosis in non-HIV infected patients presenting with haemoptysis and headache. Early recognition and administration of appropriate therapy will improve clinical outcome in these patients.


Subject(s)
Cryptococcosis/pathology , Headache/etiology , Hemoptysis/etiology , Lung Diseases, Fungal/pathology , Adult , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Cryptococcosis/complications , Cryptococcosis/drug therapy , Diagnosis, Differential , Fluconazole/therapeutic use , Humans , Lung Diseases, Fungal/complications , Lung Diseases, Fungal/drug therapy , Lung Neoplasms/pathology , Recurrence
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