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1.
Sensors (Basel) ; 23(19)2023 Sep 25.
Article in English | MEDLINE | ID: mdl-37836899

ABSTRACT

In this paper, we optimize the secrecy capacity of the legitimate user under resource allocation and security constraints for a multi-antenna environment for the simultaneous transmission of wireless information and power in a dynamic downlink scenario. We study the relationship between secrecy capacity and harvested energy in a power-splitting configuration for a nonlinear energy-harvesting model under co-located conditions. The capacity maximization problem is formulated for the vehicle-to-vehicle communication scenario. The formulated problem is non-convex NP-hard, so we reformulate it into a convex form using a divide-and-conquer approach. We obtain the optimal transmit power matrix and power-splitting ratio values that guarantee positive values of the secrecy capacity. We analyze different vehicle-to-vehicle communication settings to validate the differentiation of the proposed algorithm in maintaining both reliability and security. We also substantiate the effectiveness of the proposed approach by analyzing the trade-offs between secrecy capacity and harvested energy.

2.
BMC Cancer ; 4: 94, 2004 Dec 20.
Article in English | MEDLINE | ID: mdl-15610554

ABSTRACT

BACKGROUND: Uncertainty regarding comorbid illness, and ability to tolerate aggressive therapy has led to minimal enrollment of elderly cancer patients into clinical trials and often substandard treatment. Increasingly, comorbid illness scales have proven useful in identifying subgroups of elderly patients who are more likely to tolerate and benefit from aggressive therapy. Unfortunately, the use of such scales has yet to be widely integrated into either clinical practice or clinical trials research. METHODS: This article reviews evidence for the validity of the Charlson Comorbidity Index (CCI) in oncology and provides a Microsoft Excel (MS Excel) Macro for the rapid and accurate calculation of CCI score. The interaction of comorbidity and malignant disease and the validation of the Charlson Index in oncology are discussed. RESULTS: The CCI score is based on one year mortality data from internal medicine patients admitted to an inpatient setting and is the most widely used comorbidity index in oncology. An MS Excel Macro file was constructed for calculating the CCI score using Microsoft Visual Basic. The Macro is provided for download and dissemination. The CCI has been widely used and validated throughout the oncology literature and has demonstrated utility for most major cancers. The MS Excel CCI Macro provides a rapid method for calculating CCI score with or without age adjustments. The calculator removes difficulty in score calculation as a limitation for integration of the CCI into clinical research. The simple nature of the MS Excel CCI Macro and the CCI itself makes it ideal for integration into emerging electronic medical records systems. CONCLUSIONS: The increasing elderly population and concurrent increase in oncologic disease has made understanding the interaction between age and comorbid illness on life expectancy increasingly important. The MS Excel CCI Macro provides a means of increasing the use of the CCI scale in clinical research with the ultimate goal of improving determination of optimal treatments for elderly cancer patients.


Subject(s)
Comorbidity , Mathematical Computing , Neoplasms/mortality , Outcome Assessment, Health Care/methods , Aged , Humans , Reproducibility of Results , Risk , Treatment Outcome
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