1.
BMJ Case Rep
; 12(7)2019 Jul 19.
Article
in English
| MEDLINE
| ID: mdl-31326904
ABSTRACT
Bilateral independent periodic lateralised epileptiform discharges (BIPLEDs) in electroencephalograms (EEGs) are commonly caused by anoxic encephalopathy and central nervous system infections. They are associated with coma and high mortality and are thus markers of poor prognosis. We present a case of encephalitis who presented with BIPLEDs in EEG. Though the clinical, EEG and MRI features closely resembled herpes simplex encephalitis, further investigations proved it to be Epstein-Barr virus (EBV) encephalitis. Despite the presence of BIPLEDs in the EEG, the patient had a rapid clinical response to therapy with acyclovir. We emphasise that BIPLEDs may not always indicate poor prognosis especially in the setting of EBV encephalitis.
Subject(s)
Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Encephalitis, Viral/virology , Herpesvirus 4, Human/isolation & purification , Seizures/virology , Adult , Diagnosis, Differential , Electroencephalography , Encephalitis, Viral/diagnosis , Encephalitis, Viral/drug therapy , Humans , Magnetic Resonance Imaging , Male , Seizures/diagnosis , Seizures/drug therapy
2.
BMJ Case Rep
; 20182018 Jan 26.
Article
in English
| MEDLINE
| ID: mdl-29374643