ABSTRACT
Twenty two patients with tumours or tumour-like conditions of the para-testicular region (PTR) were diagnosed over a 5 year period. Of these, 16 (73%) were benign with only one true neoplasm (papillary cystadenoma). The tumour-like conditions were comprised of 6 cases of adenomatous hyperplasia of epididymis, 4 cases of spermatic granuloma, 2 cases each of spermatocele and nodular-fibrous proliferation and one mesothelial cyst. Three patients with spermatic granuloma gave a history of trauma. No case of adenomatoid tumour was encountered. Six malignant neoplasms were diagnosed (27%) all of which were sarcomas. Five were primary to the PTR and one was a metastatic deposit from a primary leiomyoblastoma of the mesentery. Among the 5 primary sarcomas were 2 cases each of rhabdomyosarcoma and leiomyosarcoma, and 1 case of liposarcoma. The patient with leiomyoblastoma presented first with a measenteric mass which was followed a month later by a rapidly growing mass in the scrotum. Immunohistochemical staining (IHC) and Electron microscopy (EM) were done in this case. Intra-cytoplasmic myofilaments as well as desmosomes were observed. The patients ranged from 14 to 65 years of age and most presented with painless mass in the scrotum. Follow-up was not possible due to practical difficulties.
Subject(s)
Testicular Diseases/pathology , Testicular Neoplasms/pathology , Adenoma/pathology , Cystadenoma, Papillary/pathology , Cysts/pathology , Epididymis/pathology , Granuloma/pathology , Humans , Hyperplasia , Leiomyoma/pathology , Male , Rhabdomyosarcoma/pathology , Sarcoma/pathology , Spermatocele/pathologyABSTRACT
OBJECTIVE: To identify cases of Toxoplasma lymphadenitis by light microscopic examination of fine needle aspiration cytology (FNAC) smears and paraffin sections and to correlate the result with those of serologic tests. STUDY DESIGN: The study group consisted of 19 cases of Toxoplasma lymphadenitis, 7 of which were diagnosed by FNAC, 9 on excision biopsy and 3 on FNAC followed by biopsy. Nineteen cases of reactive lymphadenitis, tuberculosis and infectious mononucleosus composed the control group. Sera from all 38 patients were screened for antibodies to Toxoplasma. RESULTS: Eleven of 19 cases (58%) of Toxoplasma adenitis had very high titers of antibody (> 300 ELISA units/ml), and 6 cases (31%) had antibody titers in a range suggestive of active infection (210-300 ELISA units/mL) and required demonstration of rising titers. Overall, 89% of patients with Toxoplasma lymphadenitis showed significant levels of antibody. All patients from the control group showed consistently low levels of antibody to Toxoplasma. CONCLUSION: Though serologic tests are mandatory for the diagnosis of Toxoplasma lymphadenitis, a high index of suspicion can be obtained by means of light microscopy alone.
Subject(s)
Antigens, Protozoan/analysis , Lymphadenitis/diagnosis , Toxoplasma/immunology , Toxoplasmosis/diagnosis , Adolescent , Adult , Animals , Biopsy , Biopsy, Needle , Child , Child, Preschool , Female , Humans , Infectious Mononucleosis/diagnosis , Lymphadenitis/pathology , Male , Middle Aged , Toxoplasmosis/immunology , Toxoplasmosis/pathology , Tuberculosis, Lymph Node/diagnosisABSTRACT
Two cases of persistence of Müllerian duct structures in phenotypic male patients are reported. One of these was aged 16 years and the other 10 months. Both patients had cryptorchidism and inguinal hernia for which they were operated upon. In both patients parts of uterus and fallopian tubes were identified in the hernial sac. Endocrine evaluation was normal. Karyotyping was performed in the second case which revealed a normal male genotype of 46 XY.
Subject(s)
Mullerian Ducts/abnormalities , Adolescent , Cryptorchidism/diagnosis , Cryptorchidism/surgery , Fallopian Tubes/growth & development , Female , Hernia, Inguinal/diagnosis , Hernia, Inguinal/surgery , Humans , Infant , Male , Syndrome , Uterus/growth & developmentABSTRACT
During a two year study period, 6163 samples of urine among a total of 10366 miscellaneous samples received for culture, were analysed. Of these 1488 samples (24.15%) showed evidence of infection. In our study, E. Coli was found most frequently (61.40%) followed by Klebsiella (17.1%). The pattern of antibiotic sensitivity was analysed. Ciprofloxacin and Norfloxacin proved to be the most promising among the new generation of antibiotics. Results with Cloxacillin, Colistin and Lincomycin were found to be disappointing. The study serves to analyse the pattern of urinary infection in our setup and also dwells upon the emergence of strains resistant to even the newer antibiotics.
Subject(s)
Urine/microbiology , Bacterial Infections/diagnosis , Bacterial Infections/drug therapy , Clinical Laboratory Techniques , Drug Resistance, Microbial , Female , Humans , Urinary Tract Infections/diagnosis , Urinary Tract Infections/drug therapyABSTRACT
Angiolymphoid hyperplasia with eosinophilia (AHE) is a rare disease entity which usually presents as subcutaneous nodules, sometimes simulating lymphadenopathy or even angiosarcoma. We present here the histopathological aspects of a case which manifested as a subcutaneous forehead nodule, along with the relevant review of literature concerning this rare entity.
