Particular features of systolic and diastolic functions in patients with metabolic syndrome.

In many epidemiological studies, the relationship between metabolic syndrome and the development of congestive heart failure has been established. Due to the latter, an increased interest has been noticed in scientific studies about the changes in the function of the heart in patients with metabolic syndrome and possible disturbance mechanisms of the pumping function of the heart in this group of patients. In our research, 120 patients with metabolic syndrome and 20 health individuals were studied. The cardiac functions were assessed with the ultrasound imaging machine "Aloka SSD 5000" (Japan) convex sensor of frequency 3.5 MHz with generally used methods. In the course of the experiment, in patients with MS, concentric hypertrophy of the heart and disturbance of the diastolic function of the heart was noticed. Also it was set that there was a significant correlation between the indexes, which in a superlative degree demonstrate abdominal obesity (WHR) and the indexes of LV hypertrophy during diastole (r = 0.72; P < 0.001), LVM (r = 0.81; P < 0.001) and LA (r = 0.63; P < 0.001).

[Particular features of fatty acids composition of low density lipiproteids in patients with metabolic syndrome].

The objective of the work was the study of particular features of fatty acid (FA) composition of the low density lipoproteids (LDL) in patients with metabolic syndrome (MS) (39,7+/-3,4 years). In patients with MS, compared to the healthy adults of the same age was revealed a significant increase in saturated FAs and significant decrease in unsaturated and polyunsaturated FAs in LDL particles. Significant correlation was revealed between indexes of abdominal adiposity, intima media thickness of arteria carotis communis, and level of some FAs in the LDLs. This changes of FA composition could be a cause of enhancing of LDL atherogenic process in patients with methabolic syndrome.