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Mikrochim Acta ; 185(10): 479, 2018 09 26.
Article in English | MEDLINE | ID: mdl-30259140

ABSTRACT

A highly selective electrochemical sensor was fabricated based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe2O4 NPs). The nanocomposite has attractive properties such as high surface-to-volume ratio and good electrocatalytic activity towards the drugs acetaminophen (AC), epinephrine (EP), and melatonin (MT), best at working voltages of 0.35, 0.09 and 0.55 V (vs. Ag/AgCl), respectively. The linear ranges (and detection limits) are 6.5-135 (0.4) µmol L-1 for AC, 5-100 (0.7) µmol L-1 for EP, and 6.5-145 (3) µmol L-1 for MT. Graphical abstract A novel electrochemical sensor based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe2O4) for the simultaneous detection of the acetaminophen, epinephrine and melatonin was fabricated.


Subject(s)
Acetaminophen/analysis , Carbon/chemistry , Electrochemistry/instrumentation , Epinephrine/analysis , Ferric Compounds/chemistry , Melatonin/analysis , Nanoparticles/chemistry , Zinc Compounds/chemistry , Electrodes , Ointments , Time Factors
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