ABSTRACT
This is a retrospective study, conducted on thyroid cancer observed for 13 months (from June 1(st) 2004 to June 30(th) 2005). Data were collected from four main surgical pathology laboratories in Antananarivo, Madagascar. Among 6,036 surgical samples, 179 were of thyroid gland, a rate that is near 3% of the total. Among them were found 40 cases of thyroid cancer, which is 0.66% of all screened samples, and 22.32% of all examined thyroid samples. In the studied population was observed a female preponderance (82%) with a mean age of 43.9 years when diagnosis was confirmed. It was evidenced a 50 % of papillary carcinoma and 45% of follicular carcinoma, with a rate of 2.5% respectively for the medullar and anaplastic carcinoma. Metastases were seen in 20%, originated from papillary type for the lymph node involvement and from the follicular type for the bone involvement. In Antananarivo, thyroid cancer is seen mainly in people from the surrounding Highlands, supposed to be sites of endemic goiter related to iodine deficiency. Despite its limits, this study may be used as reference about thyroid cancer in Madagascar. Further studies are required to find out other factors involved in the development of this disease.
Subject(s)
Thyroid Neoplasms/epidemiology , Adult , Carcinoma, Papillary/epidemiology , Carcinoma, Papillary/pathology , Carcinoma, Papillary/surgery , Ethnicity/statistics & numerical data , Female , Humans , Madagascar/epidemiology , Male , Middle Aged , Prevalence , Retrospective Studies , Sex Ratio , Thyroid Neoplasms/pathology , Thyroid Neoplasms/surgeryABSTRACT
Le rhabdomyosarcome genitale de l'enfant est rare. Il est l'apanage des enfants de moins de six ans et se voit rarement en periode neonatale. Nous rapportons un cas de tumefaction vulvaire; decouvert vers l'age de cinq mois. Le diagnostic histologique de rhabdomyosarcome n'etait pose que vers l'age d'un an. Apres exerese chirurgicale; trois cures de chimiotherapie etaient prescrites. Une recidive survenait apres cette troisieme cure et l'enfant etait par la suite perdu de vue. Malgre les avancees therapeutiques de ces dernieres annees; le pronostic des rhabdomyosarcomes vulvaires reste sombre; particulierement dans un pays en developpement. En effet; le diagnostic y est souvent tardif et le cout du traitement inaccessible pour la majorite de la population
