Infantile cortical hyperostosis with raised immumoglobulins

Two cases of infantile cortical hyperostosis are reported. Both had raised immunoglobulins. Particularly remarkable were the IgA and IgM levels, a finding infrequently reported (AU)

Anhidrotic ectodermal dysplasia in an infant presenting with pyrexia of unknown origin

Anhidrotic ectodermal dysplasia is a rare condition resulting from faulty development of the embryonic ectoderm and its derivatives. It is heredofamilial, sex linked and recessive. There may be some manifestation in the carrier female. In some families a dominant gene has been described. The disease is characterized by anhidrosis, hypotrichosis, and hypodontia. Other features commonly associated are prominent supraorbital ridges, depressed bridge of the nose, large deformed ears, fine wrinkling of the preiorbital skin, chronic rhinitis hoarseness, recurrent otitis, soft thin dry skin, and lack of body odor. The present communication describes the syndrome in a West Indian child of Spainsh-East Indian descent

Acute outbreak of para-influenza respiratory disease in children: clinical aspect

There was a sudden, severe outbreak of acute respiratory disease in North Trinidad from October - December 1967, affecting all age groups but it was particularly severe and widespread among young children under the age of three years. Southern Trinidad was not affected although there is easy communication with the north. Seventy-one strains of the para-influenza viruses have been isolated from five hundred and seventy-three patients with respiratory disease admitted to the Port-of-Spain General Hospital. The clinical features and management have been discussed. It seems likely that the virus was introduced by overseas visitors at points of entry into Trinidad. (AU)

An epidemic of para-influenza infection in Trinidad - abstract

An outbreak of acute respiratory disease occurred among infants and children in northern Trinidad during the last quarter of 1967. Between October 1 and December 31, six hundred children were admitted to Port-of-Spain General Hospital. Approximately one half of these patients were less than two years of age. Clinical syndromes ranged from severe acute upper respiratory infections to bronchitis and pneumonia. Profuse muco-purulent upper respiratory secretions and severe bronchospasm were prominent clinical manifestations. There were six deaths. Hemabsorbing agents were isolated from 60 patients. To date, 31 have been identified as para-influenza I, eight as para-influenza III and one as para-influenza II. Although para-influenza viruses have been implicated as the cause of sporadic respiratory illnesses in Trinidad in the past, the occurrence of a large outbreak due to these agents is an epidemiologic pattern not previously recognized in the Eastern Caribbean(AU)

A study of gastroenteritis admissions to a General Hospital

Nine hundred and eight admissions to the gastro-enteritis unit at Port-of -Spain hospital were studied. Factors examined included age, sex, associated disease and artificial feeding. The main lines of therapy were outlined and, future paths of investigation indicated (AU)

Epidemic and endemic pattern of childhood nephritis: pathogenesis, epidemiology and clinical course of outbreaks in Trinidad

More than 800 children with acute glomerulonephritis were admitted to one hospital in Trinidad during three and one-half years. In the first 15 months the disease was epidemic. The illness affected chiefly the children of the rural poor, with the most cases attributable to streptococcal infection of the skin rather than of the respiratory tract. In signs, symptoms and clinical course, the disease in Trinidad resembles closely the acute glomerulonephritis which follows streptoccocal pharyngitis in temperate climates. (AU)