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7.
Actas Dermosifiliogr (Engl Ed) ; 109(7): 610-616, 2018 Sep.
Article in English, Spanish | MEDLINE | ID: mdl-29680323

ABSTRACT

BACKGROUND AND OBJECTIVE: Primary cutaneous lymphomas are uncommon. This article describes the Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV) and reports on the results from the first year. PATIENTS AND METHODS: Disease registry for patients with primary cutaneous lymphoma. The participating hospitals prospectively recorded data on diagnosis, treatment, tests, and disease stage for all patients with primary cutaneous lymphoma. A descriptive analysis was performed. RESULTS: In December 2017, the registry contained data on 639 patients (60% male) from 16 university hospitals. The most common diagnoses, in order of frequency, were mycosis fungoides/Sézary syndrome (MF/SS) (348 cases, 55%), primary cutaneous B-cell lymphoma (CBCL) (184 cases, 29%), primary cutaneous CD30+ T-cell lymphoproliferative disorder (CD30+ CLPD) (70 cases, 11%), and other types of T-cell lymphoma (37 cases, 5%). In total, 105 (16.5%) of the cases recorded were incident cases. The most common diagnosis in the MF/SS group was classic MF (77.3%). Half of the patients with MF had stage IA disease when diagnosed, and the majority were either in partial remission (32.5%) or had stable disease (33.1%). The most widely used treatments were topical corticosteroids (90.8%) and phototherapy. The most common form of primary CBCL was marginal zone lymphoma (50%). Almost all of the patients had cutaneous involvement only and nearly half had stage T1a disease. Most (76.1%) were in complete remission. The main treatments were surgery (55.4%) and radiotherapy (41.9%). The most common diagnosis in patients with CD30+ CLPD was lymphomatoid papulosis (68.8%). Most of the patients (31.4%) had stage T3b disease and half were in complete remission. The most common treatments were topical corticosteroids (68.8%) and systemic chemotherapy (32.9%). CONCLUSION: The characteristics of patients with primary cutaneous lymphoma in Spain do not differ from those described in other series in the literature. The registry will facilitate clinical research by the AEDV's lymphoma group.


Subject(s)
Lymphoma, B-Cell/epidemiology , Lymphoma, T-Cell, Cutaneous/epidemiology , Registries , Skin Neoplasms/epidemiology , Databases, Factual , Humans , Lymphoma, B-Cell/diagnosis , Lymphoma, B-Cell/therapy , Lymphoma, Large-Cell, Anaplastic/epidemiology , Lymphoma, T-Cell, Cutaneous/diagnosis , Lymphoma, T-Cell, Cutaneous/therapy , Lymphomatoid Papulosis/diagnosis , Lymphomatoid Papulosis/epidemiology , Prospective Studies , Spain/epidemiology
11.
Med Cutan Ibero Lat Am ; 17(6): 357-9, 1989.
Article in Spanish | MEDLINE | ID: mdl-2699633

ABSTRACT

A 31 years old woman had an exanthematic eruption of small and acral distributed papules. At the same time she suffered a clinical and biological hepatitis B. This case is described attending to the clinic, histopathology and direct immunofluorescence. By the way the Gianotti-Crosti syndrome is reviewed.


Subject(s)
Acrodermatitis/complications , Hepatitis B/complications , Skin Diseases, Vesiculobullous/complications , Acrodermatitis/blood , Adult , Female , Hepatitis B/blood , Hepatitis B Surface Antigens/analysis , Humans , Skin Diseases, Vesiculobullous/blood , Syndrome
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