ABSTRACT
Wegener's granulomatosis (WG) is characterized by necrotizing granulomas and vasculitis that may affect any organ. The upper and lower respiratory tract and kidney usually are affected. WG is diagnosed by determination of anti-neutrophil cytoplasm antibody (ANCA), a highly sensitive and specific test that is particularly important in the early stages to achieve the best prognosis. We describe a case in a 28-year-old man that exemplifies some of the diagnostic features of WG.
Subject(s)
Granulomatosis with Polyangiitis/diagnosis , Adult , Cytoplasm/ultrastructure , Granulomatosis with Polyangiitis/complications , Humans , Male , Neutrophils/ultrastructure , Renal Insufficiency/complications , Respiratory Tract Diseases/complicationsABSTRACT
We evaluate retrospectively 38 patients with AIDS and Cytomegalovirus (CMV) retinitis. In 72.5% (45 from 62 eyes) it carried an important sight risk; 50% of the end of the follow-up. Evidence of extraocular illness in 28.5% of the patients. Using control groups the AIDS microvasculopathy is neither more frequent in CMV-retinitis nor associated with a special risk group (p greater than 0.05), we review treatment, follow-up and complications. The median survival was 6 months without significan differences (p greater than 0.05) with or without the finding of microvasculopathy, bilaterality or extraocular illness.
