[Metoclopramide as a painkiller for intense migraine headache in emergency departments]. / Metoclopramida como analgésico en la cefalea migrañosa intensa en urgencias.

INTRODUCTION: Migraine headache is an uncommon but disabling clinical entity when patients go to an urgency room with a severe migraine attack and digestive symptoms. Intravenous non-steroidal anti-inflammatory drugs, paracetamol and triptans represent the first line drugs in the migraine therapy in emergency departments elsewhere however the low efficacy and the limitations of the oral way for vomiting determine a difficult situations in some migraine patients. Metoclopramide is an anti-emetic drug which indication in migraine for vomiting and as an adjunctive drug to other analgesic has been reported elsewhere but the analgesic features of this drug in monotherapy has not been largely study in the medical literature. PATIENTS AND METHODS: We report in this article the clinical features and side effects of 14 patients with severe migraine with digestive symptoms which consecutive came to our urgency department. RESULTS AND CONCLUSIONS: The patients showed a important improvement after 10 mg of intravenous metoclopramide exclusively with no other analgesic drug.

Metoclopramida como analgésico en la cefalea migrañosa intensa en urgencias / Metoclopramide as a painkiller for intense migraine headache in emergency departments

Introducción. La cefalea de tipo migrañoso es una entidad clínica poco común pero incapacitante cuando los pacientes acuden al servicio de urgencias por una crisis migrañosa grave acompañada de síntomas digestivos. Los antiinflamatorios no esteroideos intravenosos, el paracetamol y los triptanos representan los medicamentos de primera línea en el tratamiento de la migraña en los servicios de urgencias; en otras circunstancias, sin embargo, la poca eficacia y las limitacionesde la vía oral debido a los vómitos complican la situación en algunos pacientes con migraña. La metoclopramida es un antiemético cuya indicación en la migraña para los vómitos y como fármaco complementario de otros analgésicos se ha descrito anteriormente, pero las características analgésicas de este fármaco en monoterapia no se han estudiado a fondo en las publicaciones médicas. Pacientes y métodos. En este artículo, describimos el cuadro clínico y los efectos secundarios de 14 pacientesconsecutivos que acudieron a nuestro servicio de urgencias con migraña grave y con síntomas digestivos. Resultados y conclusiones. Los pacientes mostraron una importante mejoría después de la administración intravenosa de 10 mg de metoclopramida exclusivamente, sin ningún otro analgésico

Introduction. Migraine headache is an uncommon but disabling clinical entity when patients go to an urgencyroom with a severe migraine attack and digestive symptoms. Intravenous non-steroidal anti-inflammatory drugs, paracetamol and triptans represent the first line drugs in the migraine therapy in emergency departments elsewhere however the low efficacy and the limitations of the oral way for vomiting determine a difficult situations in some migraine patients. Metoclopramide is an anti-emetic drug which indication in migraine for vomiting and as an adjunctive drug to other analgesic has been reported elsewhere but the analgesic features of this drug in monotherapy has not been largely study in the medical literature. Patients and methods. We report in this article the clinical features and side effects of 14 patients with severe migraine with digestive symptoms which consecutive came to our urgency department. Results and conclusions. The patients showed a important improvement after 10 mg of intravenous metoclopramide exclusively with no other analgesic drug

Baclofeno intratecal en la distonía generalizada secundaria a una hipoxia cerebral / Intrathecal baclofen in generalised dystonia secondary to cerebral hypoxia

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