Teeth loss and its association with locomotive syndrome among patients visiting the outpatient department of a dental school in Mahbubnagar, India-A cross sectional study.

BACKGROUND: Locomotive syndrome (LoS) is condition wherein mobility functions such as sit-to-stand or gait are declined due to locomotive organ impairment. The important risk factors for the LoS are ageing and physical factors. Physical factors significantly associated with dental status Aim: To investigate the relationships between teeth lost and locomotive syndrome. MATERIALS AND METHOD: A cross sectional study was carried among (45-90 years) individuals by using Loco Check List. Factors related to demographics (age, sex) and number of teeth lost were assessed. Pearson's chi-square test, multiple logistic regression analysis were performed. p <0.05 was considered to be statistically significant. RESULTS: Out of 322 subjects, majority of subjects (58.7%) hadLoS.Locomotive syndrome was observed high significantly (78.0% P = 0.0000) among >60 years age group. Majority of the subjects with tooth loss more than 10 teeth (92.6%) had a locomotive syndrome followed by the subjects with tooth loss 1-10 teeth (52.1%). Multiple logistic regression analysis revealed Locomotive syndrome was significantly (P= 0.000) higher among older age groups (>60 years) when compared with the 45- 60 years age group (or = 0.732) and subject with more than 10 teeth lost when compared with others (or = .009,or = 0.105) Conclusion: Study indicates that older age and number of teeth lost affect the prevalence of locomotive syndrome. Hence, maintaining oral health is necessary to retain more number of teeth throughout life which reduces the risk of locomotive syndrome.

Locally delivered antioxidant gel as an adjunct to nonsurgical therapy improves measures of oxidative stress and periodontal disease

PURPOSE: The present study has two aims; firstly, it attempts to verify the presence of oxidative stress by estimating the reactive oxygen species (ROS) levels in periodontal pockets > or =5 mm as compared to controls. The second aim is to evaluate the effect of lycopene as a locally delivered antioxidant gel on periodontal health and on the gingival crevicular fluid (GCF) levels of 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative injury. METHODS: Thirty-one subjects participated in this study. In the pretreatment phase, the ROS levels in pockets > or =5 mm were measured by flow cytometry. Three sites in each subject were randomly assigned into each of the following experimental groups: sham group, only scaling and root planing (SRP) was done; placebo group, local delivery of placebo gel after SRP; and lycopene group, local delivery of lycopene gel after SRP. Clinical parameters included recording site-specific measures of GCF 8-OHdG, plaque, gingivitis, probing depth, and clinical attachment level. RESULTS: The gel, when delivered to the sites with oxidative stress, was effective in increasing clinical attachment and in reducing gingival inflammation, probing depth, and 8-OHdG levels as compared to the placebo and sham sites. CONCLUSIONS: From this trial conducted over a period of 6 months, it was found that locally delivered lycopene seems to be effective in reducing the measures of oxidative stress and periodontal disease.