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1.
J Clin Anesth ; 25(6): 475-82, 2013 Sep.
Article in English | MEDLINE | ID: mdl-24012493

ABSTRACT

STUDY OBJECTIVE: To determine whether transversus abdominis plane (TAP) blocks administered in conjunction with intrathecal morphine provided superior analgesia to intrathecal morphine alone. DESIGN: Randomized, double-blind, placebo-controlled study. SETTING: Operating room of a university hospital. PATIENTS: 51 women undergoing elective Cesarean delivery with a combined spinal-epidural technique that included intrathecal morphine. INTERVENTIONS: Subjects were randomized to receive a bilateral TAP block with 0.5% ropivacaine or 0.9% saline. Postoperative analgesics were administered on request and selected based on pain severity. MEASUREMENTS: Patients were evaluated at 2, 24, and 48 hours after the TAP blocks were performed. Verbal rating scale (VRS) pain scores at rest, with movement, and for colicky pain were recorded, as was analgesic consumption. Patients rated the severity of opioid side effects and their satisfaction with the procedure and analgesia. MAIN RESULTS: 51 subjects received TAP blocks with ropivacaine (n = 26) or saline (n = 25). At two hours, the ropivacaine group reported less pain at rest and with movement (0.5 and 1.9 vs 2.8 and 4.9 in the saline group [VRS scale 0 - 10]; P < 0.001) and had no requests for analgesics; there were several requests for analgesia in the saline group. At 24 hours, there was no difference in pain scores or analgesic consumption. At 48 hours, the ropivacaine group received more analgesics for moderate pain (P = 0.04) and the saline group received more analgesics for severe pain (P = 0.01). CONCLUSIONS: Transversus abdominis plane blocks in conjunction with intrathecal morphine provided superior early postcesarean analgesia to intrathecal morphine alone. By 24 hours there was no difference in pain scores or analgesic consumption.


Subject(s)
Analgesia, Obstetrical/methods , Analgesics, Opioid/administration & dosage , Cesarean Section , Morphine/administration & dosage , Nerve Block/methods , Pain, Postoperative/prevention & control , Abdominal Muscles/diagnostic imaging , Abdominal Muscles/innervation , Adult , Amides/administration & dosage , Anesthetics, Local/administration & dosage , Double-Blind Method , Female , Humans , Infusions, Spinal , Kaplan-Meier Estimate , Pain Measurement/methods , Pregnancy , Ropivacaine , Ultrasonography, Interventional/methods , Young Adult
2.
Acta Anaesthesiol Scand ; 52(1): 6-19, 2008 Jan.
Article in English | MEDLINE | ID: mdl-18173431

ABSTRACT

BACKGROUND: The incidence of obesity has been dramatically increasing across the globe. Anesthesiologists, are increasingly faced with the care for these patients. Obesity in the pregnant woman is associated with a broad spectrum of problems, including dramatically increased risk for cesarean delivery, diabetes, hypertension and pre-eclampsia. A thorough understanding of the physiology, associated conditions and morbidity, available options for anesthesia and possible complications is therefore important for today's anesthesiologist. METHODS: This is a personal review in which different aspects of obesity in the pregnant woman, that are relevant to the anesthesiologist, are discussed. An overview of maternal and fetal morbidity and physiologic changes associated with pregnancy and obesity is provided and different options for labor analgesia, the anesthetic management for cesarean delivery and potential post-partum complications are discussed in detail. RESULTS AND CONCLUSION: The anesthetic management of the morbidly obese parturient is associated with special hazards. The risk for difficult or failed intubation is exceedingly high. The early placement of an epidural or intrathecal catheter may overcome the need for general anesthesia, however, the high initial failure rate necessitates critical block assessment and catheter replacement when indicated.


Subject(s)
Anesthesia, Obstetrical/methods , Obesity/physiopathology , Pregnancy Complications/physiopathology , Adult , Anesthesia, Epidural/adverse effects , Anesthesia, Epidural/methods , Anesthesia, General/adverse effects , Anesthesia, General/methods , Anesthesia, Obstetrical/adverse effects , Anesthesia, Spinal/adverse effects , Anesthesia, Spinal/methods , Cesarean Section , Continuous Positive Airway Pressure , Death, Sudden, Cardiac/etiology , Death, Sudden, Cardiac/prevention & control , Dyspnea/etiology , Dyspnea/physiopathology , Female , Fetal Diseases/prevention & control , Hemodynamics , Humans , Obesity, Morbid/physiopathology , Obstetric Labor Complications/physiopathology , Postoperative Complications/prevention & control , Pregnancy , Puerperal Disorders/prevention & control , Respiratory Aspiration/prevention & control , Respiratory Mechanics , Risk
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