ABSTRACT
Obstructive sleep apnea has been associated with various cardiac arrhythmias; however, supraventricular tachycardia has not been reported to occur in this disorder. This case report describes a patient who developed episodes of supraventricular tachycardia during periods of apnea and oxygen desaturation. With the initiation of nasal continuous positive airway pressure during sleep, the arrhythmia was abolished. The etiology and possible mechanisms responsible for the supraventricular tachycardia are discussed.
Subject(s)
Hypoxia/complications , Sleep Apnea Syndromes/complications , Tachycardia, Supraventricular/etiology , Adult , Electrocardiography , Female , Humans , Hypoxia/metabolism , Sleep Apnea Syndromes/metabolism , Tachycardia, Supraventricular/metabolism , Tachycardia, Supraventricular/physiopathologyABSTRACT
A case of complete atrioventricular block with ventricular asystole in a patient receiving intravenous phenytoin is presented. Although the potential for hypotension is generally recognized with the intravenous administration of phenytoin, conduction abnormalities are rarely reported. The differential diagnosis of atrioventricular block and the effects of phenytoin on cardiac conduction are discussed.
Subject(s)
Heart Arrest/chemically induced , Heart Block/chemically induced , Phenytoin/adverse effects , Aged , Electrocardiography , Female , Heart Arrest/physiopathology , Heart Block/physiopathology , Humans , Infusions, Intravenous , Phenytoin/administration & dosageABSTRACT
Wide complex tachycardias may represent a rare proarrhythmic effect of some antiarrhythmic agents. The authors describe a patient who developed a wide complex tachycardia developing during stress testing while on therapy with flecainide, and the difficulty in interpreting the electrocardiogram. This article reviews potential proarrhythmic effects of flecainide in the treatment of atrial dysrhythmias and the difficulty in differentiating associated wide complex tachycardias.
Subject(s)
Bundle-Branch Block/chemically induced , Flecainide/adverse effects , Physical Exertion/physiology , Tachycardia/chemically induced , Ventricular Function/drug effects , Aged , Atrial Function/drug effects , Diagnosis, Differential , Electrocardiography/drug effects , Exercise Test , Humans , MaleABSTRACT
Antibodies were compared for use in the spin-amplified shell vial method for rapid cytomegalovirus detection. Commercial antibodies by Du Pont Co., Whittaker M.A. Bioproducts, Bartels Immunodiagnostic, Virostat, and Serono Diagnostics were compared at incubation times of 16 to 48 h on 22 patient specimens. Only the Du Pont antibody showed 100% sensitivity and specificity and no nonspecific reactions.
