1.
Rev Med Brux
; 28(2): 119-22, 2007.
Article
in French
| MEDLINE
| ID: mdl-17561726
ABSTRACT
We describe here a very rare congenital malformation, in which the vertebra Th 9 to 11 were divided into independent bodies and neural arches. The vertebral canal contained the spinal cord, whereas the space between bodies and arches was filled by nerve roots and a central remnant cord, not clearly connected to the main spinal cord. This malformation was considered as related to a fetal alcohol syndrome, with craniofacial and genitourinary abnormalities. The authors analyze, moreover the possible role of abnormal Sonic Hedgehog gene patterning in the pathogeny of this complex malformative sequence.
Subject(s)
Abnormalities, Multiple/etiology , Spinal Canal/abnormalities , Child, Preschool , Female , Fetal Alcohol Spectrum Disorders/genetics , Hedgehog Proteins/genetics , Humans , Male , Pregnancy , Radiography , Spinal Canal/diagnostic imaging , Spinal Canal/growth & development , Spinal Cord/abnormalities , Spinal Cord/diagnostic imaging , Spinal Cord/growth & development
2.
Pediatrics
; 109(6): 1185-6; author reply 1185-6, 2002 Jun.
Article
in English
| MEDLINE
| ID: mdl-12042567