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Citriquinones A and B, new benzoquinones from Penicillium citrinum.
Ranji, P K Vinitha; Wijeyaratne, S Chandrani; Jayawardana, K Hector; Gunaherath, G M Kamal B.
Nat Prod Commun ; 8(10): 1431-4, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24354194

ABSTRACT

Two new benzoquinones, citriquinone A (1) and B (2), were isolated from the methanol extract of a soil fungus, Penicillium citrinum. The structures of the new compounds were determined on the basis of detailed spectroscopic analysis. Citriquinone A (1) exhibited antibacterial activity against Bacillus sp. and cell migration inhibitory activity (CMIA) against human cancer cell line HEp 2.


Subject(s)
Antineoplastic Agents/isolation & purification , Benzoquinones/isolation & purification , Penicillium/chemistry , Antineoplastic Agents/chemistry , Antineoplastic Agents/pharmacology , Bacillus , Benzoquinones/chemistry , Benzoquinones/pharmacology , Cell Line, Tumor , Cell Movement/drug effects , Drug Screening Assays, Antitumor , Humans , Microbial Sensitivity Tests
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