1.
Org Biomol Chem
; 15(15): 3130-3151, 2017 Apr 11.
Article
in English
| MEDLINE
| ID: mdl-28338704
ABSTRACT
ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic compounds having a quaternary carbon center. Furthermore, these compounds also serve as a handy synthon for the construction of various complex molecules. This review presents various useful approaches for the intramolecular ipso-cyclization to afford a wide range of spirocyclohexadienones. In addition, the utility of spirocyclic compounds towards the synthesis of complex molecules is also included.