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1.
Biol Trace Elem Res ; 200(5): 2017-2024, 2022 May.
Article in English | MEDLINE | ID: mdl-34269974

ABSTRACT

This study was carried out to assess the efficacy of sodium iron EDTA (NaFeEDTA) salt-enriched fish powder in addressing iron deficiency in adolescent anaemic girls. This was a 60-day randomised double-blinded, controlled intervention trial involving 123 girls age ranging from 10 to 19 years in three villages of West Jaintia Hills District of State of Meghalaya in India using soup made out of sodium iron EDTA (NaFeEDTA)-enriched fish powder (250 mg/100 g). The influence of the iron-enriched powder on blood haemoglobin levels and serum iron was determined. The research also analysed the food consumed by the study subjects during the study period and it was found that there were no significant differences between the iron-enriched and control groups. The results indicated that the girls predominantly consumed cereals with little fruits, vegetables and meat. On an average, 100 ml of soup prepared out of 10 g of fish powder per day was consumed that theoretically provided about 25 mg of iron each day. Following intervention, all the participants in the group that consumed soup made out of NaFeEDTA-enriched fish powder had significantly higher haemoglobin levels and serum iron and a lower prevalence of anaemia than the control group. The effects of NaFeEDTA salt-enriched fish powder were statistically significant and it can be inferred that NaFeEDTA-enriched fish powder was highly effective in controlling iron deficiency and reducing the prevalence of iron-deficiency anaemia among the adolescent girls.


Subject(s)
Anemia, Iron-Deficiency , Anemia , Iron Deficiencies , Adolescent , Anemia, Iron-Deficiency/drug therapy , Anemia, Iron-Deficiency/epidemiology , Animals , Fishes , Food, Fortified , Hemoglobins/analysis , Humans , Iron , Powders
2.
Indian J Psychiatry ; 61(Suppl 4): S768-S772, 2019 Apr.
Article in English | MEDLINE | ID: mdl-31040471

ABSTRACT

Homeless persons with mental illness (HPMI) suffer indignities due to shirking of all obligations by the society. In addition, the HPMI is denied all rights available to citizens, such as confidentiality, privacy, safety, right to practice religion, health, and the right to not suffer from inhuman treatment. In this context, the new Mental Healthcare Act (MHCA), 2017 has brought in a list of rights for HPMI, and this is a welcome sign. The MHCA has also taken away the mandated involvement of judiciary to provide care for the HPMI. However, the ground realities in terms of the systems and the existent infrastructure are far from satisfactory to handle the issue in India. The onus of providing care for the HPMI has shifted to the state, and the public agencies are responsible for ensuring the same. The article aims to look at various sections of the MHCA relevant in regard to providing care for the HPMI.

3.
J Am Board Fam Med ; 30(6): 832-834, 2017.
Article in English | MEDLINE | ID: mdl-29180560

ABSTRACT

The antidiarrheal loperamide has had a recent, drastic increase in off-label use as an alternative treatment for symptoms of opioid withdrawal. The concept of this is easily discovered on the Internet and social media, where there are multiple blogs and forums promoting loperamide use at doses of 70 to 200 mg per day. Unfortunately, the serious side effects are not well recognized. Multiple cases of cardiac dysrhythmias contributing to death have been highlighted in recent literature. In November 2016, the US Food & Drug Administration released a statement highlighting the potential heart effects and risk of death with high doses of loperamide.1 This case regards a 22-year-old who took 200 mg of loperamide per day for 2 years as an alternative to methadone in her attempts to wean off heroin. Her subsequent spontaneous collapse, dysrhythmias, and acute hospital treatment are reviewed in detail as they were contradictory to standard therapy and required a multidisciplinary approach. Her outpatient management addressed the complex biological, psychological, and social aspects of her addiction.


Subject(s)
Analgesics, Opioid/adverse effects , Arrhythmias, Cardiac/chemically induced , Loperamide/adverse effects , Off-Label Use , Substance Withdrawal Syndrome/drug therapy , Adult , Arrhythmias, Cardiac/diagnosis , Dose-Response Relationship, Drug , Electrocardiography , Female , Humans , Loperamide/therapeutic use , Self Medication/adverse effects , Young Adult
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