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1.
BMJ Case Rep ; 14(1)2021 Jan 18.
Article in English | MEDLINE | ID: mdl-33462049

ABSTRACT

Hip dislocations are common orthopaedic emergencies which need early intervention to have a better outcome. They usually occur as a result of high energy trauma with motor vehicle accidents being the most common cause followed by fall from height. Posterior hip dislocation is more common than anterior. However, bilateral hip dislocations are rare compared with unilateral. Here we report our case with bilateral posterior hip dislocation with one side having head of femur fracture and contralateral side acetabulum fracture. Both hips were reduced under general anaesthesia on the same day of the trauma. Staged definitive treatment was carried out. The patient had an early recovery with no complications. This case represents an unusual, type of injury resulting from a high speed motor vehicle accident. Early diagnosis, immediate resuscitation and reduction of the hip joints followed by a careful and planned definitive treatment is necessary to have a better outcome.


Subject(s)
Acetabulum/injuries , Femur Head/injuries , Hip Dislocation/diagnostic imaging , Hip Dislocation/etiology , Hip Fractures/diagnostic imaging , Hip Fractures/etiology , Accidents, Traffic , Adult , Hip Dislocation/surgery , Hip Fractures/surgery , Humans , Male
2.
J Cancer Res Ther ; 16(4): 926-929, 2020.
Article in English | MEDLINE | ID: mdl-32930143

ABSTRACT

Benign and malignant bone tumors arise in small bones of the hands and feet. Nevertheless, secondary deposits at these sites are extremely rare. We report a peculiar case of an adult man who presented with thumb swelling, which was later discovered to be a metastasis from renal cell carcinoma. Such cases have a sinister prognosis with a survival rate of 6-12 months from the time of diagnosis. We intend to discuss the diagnostic dilemma and treatment of acrometastases.


Subject(s)
Bone Neoplasms/secondary , Carcinoma, Renal Cell/diagnosis , Kidney Neoplasms/diagnosis , Lung Neoplasms/secondary , Thumb/pathology , Bone Neoplasms/diagnosis , Bone Neoplasms/surgery , Carcinoma, Renal Cell/pathology , Carcinoma, Renal Cell/surgery , Humans , Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Lung Neoplasms/diagnosis , Lung Neoplasms/surgery , Male , Middle Aged , Prognosis
3.
Crit Rev Eukaryot Gene Expr ; 28(1): 87-92, 2018.
Article in English | MEDLINE | ID: mdl-29773017

ABSTRACT

Considered as a chronic illness, gastroesophageal reflux disease (GERD) has manifested itself as a widespread condition throughout the adult population. As a growing epidemic, GERD has reached a staggering prevalence of 10% to 20% in the Western world, by affecting up to 30 million people in the United States alone. Sixty percent of individuals in an adult population will experience symptoms and the impact of GERD over a period of 12 months, whereas a remarkable 20% to 30% of individuals will have weekly symptoms. This rapid increase in the prevalence of the disease requires equally rapid management techniques. Although the disease itself has no cure, management of symptoms and certain pharmacological and surgical advancements have allowed for individuals affected by GERD to receive specific treatment options sufficient for them to live a healthy life. In this paper, such management options will be examined and discussed in reference to their effectiveness in treating the symptoms presented in GERD patients.


Subject(s)
Gastroesophageal Reflux/drug therapy , Chronic Disease/drug therapy , Chronic Disease/epidemiology , Gastroesophageal Reflux/epidemiology , Humans , United States/epidemiology
4.
Indian J Physiol Pharmacol ; 56(4): 375-81, 2012.
Article in English | MEDLINE | ID: mdl-23781658

ABSTRACT

OBJECTIVE: Fixed drug combinations are a major marketing strategy in India but it can compromise the rational use of medicines. In this study we compared the fixed drug combinations and dosage forms in the hospital pharmacy before and after introducing the essential drug list. We also compared the Hospital Essential Drug List (HEDL) 2011 with the World Health Organization (WHO) Essential Drug List (EDL) 2011 and the National Essential Drug List of India (NEDL) 2011. METHODS: The study was done in a secondary level care charity hospital at Anantapur, AP with a bed size of 315 and an average OP per day of 1200-1700 visits. We compared the three essential drug lists (HEDL, WHOEDL and NEDL) and the hospital drug list before introducing EDL. Drugs which were present in NEDL and not present in the HEDL were also screened. Microsoft excel was used to tabulate the results and for graphs. RESULTS: The number of medicines used in the hospital before and after the introduction of the HEDL was 1627 and 424 respectively. On comparison, WHOEDL 2011 have 350 and NEDL of India have 348 medicines. While preparing the HEDL, 46 double drug combinations decreased to 15 and 9 triple drug combinations decreased to 1. In the case of injections, 20 double drug combinations decreased to 6 and 1 triple drug combination increased to 2. The number of tablets, capsules, injections, syrups, powders and inhalers was reduced to almost half. The great reductions were in 51 ointments to 9, 69 drops to 5, 11 paste to 0, 21 solutions to 3 and 14 creams to 1. The dosage forms removed included elixirs, insulin pens, gums, paste, paints, gargles and mouthwashes. CONCLUSIONS: There was drastic reduction in the number of medicines and dosage forms when the HEDL was implemented. Many of the fixed drug combinations were also removed for improving the rational use of medicines. The WHO essential drug list 2011, national essential drug list of India 2011 and the hospital essential drug list 2011 were comparable with few exceptions.


Subject(s)
Drugs, Essential , Hospitals, Rural , India , Secondary Care , World Health Organization
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