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Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India.
Muthusamy, Dheepa; Rao, Sitara S; Ramani, Sasirekha; Monica, Bindhu; Banerjee, Indrani; Abraham, Ooriapadickal C; Mathai, Dilip C; Primrose, Beryl; Muliyil, Jayaprakash; Wanke, Christine A; Ward, Honorine D; Kang, Gagandeep.
J Clin Microbiol ; 44(2): 632-4, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16455931

ABSTRACT

This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.


Subject(s)
AIDS-Related Opportunistic Infections/parasitology , Cryptosporidiosis/parasitology , Cryptosporidium/classification , HIV Infections/complications , Adult , Animals , Cryptosporidium/genetics , Cryptosporidium/isolation & purification , DNA, Protozoan/analysis , Genotype , Humans , India , Molecular Sequence Data , Polymerase Chain Reaction , Polymorphism, Restriction Fragment Length , Protozoan Proteins/genetics , Sequence Analysis, DNA
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