Subject(s)
Gallium Radioisotopes/analysis , Neoplasm Recurrence, Local/diagnostic imaging , Octreotide/analogs & derivatives , Organometallic Compounds/analysis , Positron Emission Tomography Computed Tomography , Radiopharmaceuticals/analysis , Solitary Fibrous Tumor, Pleural/diagnostic imaging , Aged , Female , Humans , Neoplasm Recurrence, Local/surgery , Octreotide/analysis , Solitary Fibrous Tumor, Pleural/surgeryABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Pleural Neoplasms/diagnostic imaging , Mesothelioma/diagnostic imaging , Neoplasm Metastasis/diagnostic imaging , Positron Emission Tomography Computed Tomography/methodsABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Pneumoconiosis/complications , Pneumoconiosis , Methadone/adverse effects , Lung Neoplasms , Positron-Emission Tomography/instrumentation , Positron-Emission Tomography/methods , Positron-Emission Tomography , Fluorodeoxyglucose F18 , Fentanyl/therapeutic use , Midazolam/therapeutic use , Prescription Drug Misuse/adverse effects , Bronchoscopy/methods , Bronchoscopy/trends , Bronchoscopy , Psychomotor Agitation/complications , Biopsy, NeedleSubject(s)
Granuloma, Foreign-Body/diagnostic imaging , Lung Diseases/diagnostic imaging , Methadone/adverse effects , Narcotics/adverse effects , Substance-Related Disorders/complications , Adult , Granuloma, Foreign-Body/etiology , Humans , Lung Diseases/etiology , Lung Neoplasms/diagnostic imaging , Male , Positron Emission Tomography Computed Tomography , Positron-Emission TomographyABSTRACT
No disponible
Subject(s)
Humans , Male , Aged , Nerve Sheath Neoplasms , Thoracic Neoplasms , Fluorodeoxyglucose F18 , Positron-Emission Tomography/methods , Neoplasm Metastasis , Incidental FindingsSubject(s)
Muscle Neoplasms/diagnostic imaging , Neoplasms, Multiple Primary/diagnostic imaging , Neurilemmoma/diagnostic imaging , Positron Emission Tomography Computed Tomography , Thoracic Neoplasms/diagnostic imaging , Aged , Biomarkers, Tumor , Diagnosis, Differential , Fluorine Radioisotopes , Fluorodeoxyglucose F18 , Humans , Incidental Findings , Leg , Male , Muscle Neoplasms/chemistry , Muscle Neoplasms/pathology , Neoplasms, Multiple Primary/chemistry , Neoplasms, Multiple Primary/pathology , Neurilemmoma/chemistry , Neurilemmoma/pathology , Radiopharmaceuticals , Sarcoma/diagnostic imaging , Thoracic Neoplasms/chemistry , Thoracic Neoplasms/pathologyABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Bronchial Neoplasms , Carcinoma, Bronchogenic , Lung Neoplasms , Neoplasms, Multiple Primary , Fluorodeoxyglucose F18 , Positron Emission Tomography Computed Tomography/methodsSubject(s)
Antineoplastic Agents, Hormonal/therapeutic use , Breast Neoplasms/diagnosis , Breast Neoplasms/drug therapy , Carcinoma, Ductal, Breast/diagnosis , Carcinoma, Neuroendocrine/diagnosis , Carcinoma, Neuroendocrine/drug therapy , Diagnostic Errors , Lymphatic Metastasis/pathology , Cytodiagnosis , Female , Humans , Letrozole , Mastectomy , Middle Aged , Nitriles/therapeutic use , Tamoxifen/therapeutic use , Triazoles/therapeutic useABSTRACT
Solitary fibrous tumor of the pleura (SFTP) is an uncommon entity, generally with an indolent behavior. Nevertheless, some malignant forms have been rarely reported. These, often have an aggressive biological behavior with pathological findings of invasiveness. The preoperative diagnosis and evaluation of the grade of malignancy are extremely challenging. Herein we report a case of a 64-year-old man who presented with a left giant intra-thoracic mass imaged with fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG/PET-CT) and sampled via fine-needle aspiration biopsy (FNAB). Imaging and FNAB findings showed suspicion of a benign form of SFTP. Surgical radical resection of the giant mass was performed. The definitive histological diagnosis showed a malignant SFTP. Based on this report, we take the opportunity to briefly discuss the insidious pitfalls concerning the radiological and 18F-FDG/PET-CT features as well as cyto/histological findings in the pre-operative diagnostic work-up examination of this rare entity (AU)
El tumor fibroso solitario de la pleura (TFSP) es una entidad poco frecuente, en general con un comportamiento indolente. Sin embargo, algunas formas malignas rara vez han sido publicadas, presentando a menudo un comportamiento biológico agresivo con hallazgos patológicos de invasión. El diagnóstico preoperatorio y la evaluación del grado de malignidad es extremadamente difícil. Presentamos el caso de un paciente de 64 años de edad con una masa intratorácica gigante. Se realizó TC, 18F-FDG/PET-TC y biopsia por aspiración con aguja fina. Los hallazgos de imagen y de la biopsia hacían sospechar de una forma benigna de TFSP. Se realizó la resección quirúrgica radical de la masa gigante. El diagnóstico histológico definitivo mostró el TFSP maligno. Aprovechamos la oportunidad de este caso para revisar los aspectos relativos a los estudios radiológicos, características de la 18F-FDG/PET-TC y los hallazgos cito-histológicos en la evaluación preoperatoria de esta rara entidad (AU)
Subject(s)
Humans , Giant Cell Tumors/pathology , Pleural Neoplasms/pathology , Solitary Fibrous Tumor, Pleural/pathology , Positron-Emission Tomography/methods , Fluorodeoxyglucose F18 , Preoperative Care/methods , Biopsy, Fine-NeedleABSTRACT
Solitary fibrous tumor of the pleura (SFTP) is an uncommon entity, generally with an indolent behavior. Nevertheless, some malignant forms have been rarely reported. These, often have an aggressive biological behavior with pathological findings of invasiveness. The preoperative diagnosis and evaluation of the grade of malignancy are extremely challenging. Herein we report a case of a 64-year-old man who presented with a left giant intra-thoracic mass imaged with fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG/PET-CT) and sampled via fine-needle aspiration biopsy (FNAB). Imaging and FNAB findings showed suspicion of a benign form of SFTP. Surgical radical resection of the giant mass was performed. The definitive histological diagnosis showed a malignant SFTP. Based on this report, we take the opportunity to briefly discuss the insidious pitfalls concerning the radiological and (18)F-FDG/PET-CT features as well as cyto/histological findings in the pre-operative diagnostic work-up examination of this rare entity.
Subject(s)
Fluorodeoxyglucose F18 , Multimodal Imaging , Positron-Emission Tomography , Radiopharmaceuticals , Solitary Fibrous Tumor, Pleural/diagnosis , Tomography, X-Ray Computed , Humans , Male , Middle Aged , Preoperative Care , Solitary Fibrous Tumor, Pleural/surgeryABSTRACT
AIM: Recent studies have reported a high incidence of perioperative in-stent trombosis with myocardial infarction (MI), in patients undergoing non-cardiac surgery, early after coronary angioplasty and stenting. The short and long-term results of surgery for non-small cell lung cancer (NSCLC) after prophylatic coronary angioplasty and stenting were analyzed. METHODS: Prospective collected data were examined for postoperative complications and long-term survival in 16 consecutive patients who underwent mayor lung resection for NSCLC after prophylactic coronary angioplasty and stenting for significant coronary artery disease , from 2001 to 2008. One and two non-drug-eluting stents were placed in 75% or (25% of the patient, respectively. All patients had four weeks of dual antiplatelet therapy, that was discontinued 5 days prior to surgery and replaced by low molecular weight heparin. Patients were keep sedated and intubated overnight, according to our protocol. RESULTS: There were no postoperative deaths nor MI. A patient experienced pulmonary embolism with moderate troponin release and underwent coronary angiography that showed patency of the stent. Two patients developed postoperative bleeding complications haemothorax requiring a re-thoracotomy in 1, gastric bleeding requiring blood transfusion in 1. At the mean follow-up of 30 months (range 3-95), none of the patients showed evidence of myocardial ischemia, while 5 (31%) patients died, mostly (N.=4) due to distant metastasis. The five-year survival rate was 53%. CONCLUSION: In contrast to previous reports, lung resection after prophylactic coronary angioplasty and stenting is a safe and effective treatment for NSCLC and myocardial ischemia. The application of a refined protocol could be the key factor for improved results.
Subject(s)
Angioplasty, Balloon, Coronary , Carcinoma, Non-Small-Cell Lung/surgery , Coronary Artery Disease/therapy , Lung Neoplasms/surgery , Pneumonectomy , Stents , Aged , Carcinoma, Non-Small-Cell Lung/complications , Coronary Artery Disease/complications , Female , Follow-Up Studies , Humans , Lung Neoplasms/complications , Male , Middle Aged , Prospective Studies , Risk Factors , Survival Analysis , Treatment OutcomeABSTRACT
AIM: The aim of this study was to evaluate if transpleural diagnostic methods as percutaneous fine-needle aspiration biopsy (FNAB) or tumour wedge resection by video-assisted thoracoscopic surgery (VATS) impact on local recurrence and long term survival of patients affected by non-small cell lung cancer (NSCLC). METHODS: Records concerning 179 patients with peripheral c-Ia NSCLC who underwent complete resection from 1994 to 2000 have been reviewed. Patients were randomized into two groups according to the diagnostic method employed, as follows: in group I (N.=63) diagnosis was obtained by bronchoscopy; in group II (N.=116) diagnosis was obtained by FNAB (N.=59) or tumour wedge resection by VATS (N.=57) after a negative bronchoscopy. Survival curves were compared using log-rank test. Distribution of frequencies was analyzed with Chi-square and Fisher's exact test. RESULTS: The two groups of patients did not significantly differ in terms of age, gender, forced expiratory volume in 1 second, comorbidities, histological type and tumour size; pathologic stage IIb was more frequent in group I. At a median follow-up of 48 months, (range 2-108 months), local recurrence was found in 9.5% (N.=6) of the patients in group I and in 12.5% (N.=15) of patients in group II (P=NS); distant metastasis were found in 28.6% (N.=18) of patients in group I and in 13.8% (N.=16) in group II (P=0.03). Patients in group II had a statistically better five-year survival rate than patients in group I (70% and 55% respectively P=0.016). CONCLUSION: FNAB and tumour wedge resection by VATS represent valuable diagnostic methods for lung cancers, since they do not seem to increase the risk of local recurrence. On the other hand, tumours diagnosed by bronchoscopy have a worse prognosis, that may be related to their higher metastatic potential rather than to diagnostic procedure itself.
