Subject(s)
HIV Infections/diagnosis , Immune Reconstitution Inflammatory Syndrome/diagnosis , Tuberculosis/diagnosis , Anti-HIV Agents/therapeutic use , Antitubercular Agents/therapeutic use , HIV Infections/complications , HIV Infections/drug therapy , Humans , Immune Reconstitution Inflammatory Syndrome/complications , Immune Reconstitution Inflammatory Syndrome/drug therapy , Tuberculosis/complications , Tuberculosis/drug therapyABSTRACT
Bacteria belonging to the genus Listeria have been isolated from food products of animal, plant, and fish origin, and are associated with infections in immunocompromised hosts, pregnant women, and infants. The species Listeria grayi has rarely been reported as a human pathogen. It has a unique antibiotic sensitivity profile. We describe a case of L. grayi bacteremia in a heart transplant recipient. The organism demonstrated a reduced sensitivity to ampicillin. The patient was successfully treated with a combination of vancomycin and ciprofloxacin.
Subject(s)
Bacteremia/diagnosis , Bacteremia/drug therapy , Heart Transplantation , Listeriosis/diagnosis , Listeriosis/drug therapy , Ampicillin/therapeutic use , Anti-Bacterial Agents/therapeutic use , Bacteremia/etiology , Cardiomyopathies/surgery , Food Microbiology , Gastroenteritis/complications , Gastroenteritis/microbiology , Humans , Listeriosis/complications , Male , Microbial Sensitivity Tests , Middle Aged , Myocardial Ischemia/surgery , Treatment Outcome , Vancomycin/therapeutic useABSTRACT
The immunoperoxide (IP) technique can be used for the detection of immune deposits in various tissue pathologies. This article focusses on the standardization of the reagents anti IgG, anti IgA and anti C3C which are used to target these immune deposits. Lymph node tissue was used as substrate for standardization of anti IgG and anti IgM. For anti IgA, intestine was used while for anti C3C kidney tissue rapidly proliferating glomerulo nephritis - RPGN was utilized. Sensitivity of the technique was found to be high. Also the results on paraffin section were excellent and could be interpreted using simple light microscope. It is concluded that once standardization is achieved, IP can be used as an essential modality in the detection of immune deposits in a wide variety of immunologically mediated dermatologic disorders.
