1.
Chem Commun (Camb)
; 52(85): 12582-12585, 2016 Oct 18.
Article
in English
| MEDLINE
| ID: mdl-27722284
ABSTRACT
Administration of enantiomerically pure ß-adrenergic agonists and antagonists increases their activity and reduces side effects. We report here a small-molecule artificial receptor (SMAR) that, by mimicking the ß-adrenergic receptor, is able to enantioselectively extract commercial ß-adrenergic interacting drugs. The selectivity is justified according to DFT calculations and X-ray diffraction experiments.