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1.
Expert Rev Endocrinol Metab ; 19(3): 287-294, 2024 May.
Article in English | MEDLINE | ID: mdl-38117226

ABSTRACT

BACKGROUND: Public knowledge about the role of lifestyle in managing type two diabetes (T2D) is an essential preventive strategy. Despite efforts in public awareness, the prevalence continues to rise, with the majority relying on the availability of effective therapeutics, underestimating the role of healthy lifestyle changes. This study aims to assess public awareness of the impact of lifestyle modification in managing T2D in a major metropolitan city in Saudi Arabia, which will help inform the health management authority in the country on the level of public awareness and advise on the development of educational programs. METHODS: An observational cross-sectional survey study comprising 16 knowledge and 6 attitude questions was conducted among the population over 18 years old using online survey. After validation, the online self-developed questionnaire was distributed through social media. RESULTS: The knowledge and attitude scores were similar between males and females. Participants with a family member or friend with T2D demonstrated higher knowledge scores. However, the attitude scores did not differ significantly based on family or friend relationships. CONCLUSION: The knowledge and attitude on the role of lifestyle modifications in preventing and managing T2D is moderate, implying an opportunity for innovative strategies to raise public knowledge and attitude.


Subject(s)
Diabetes Mellitus, Type 2 , Health Knowledge, Attitudes, Practice , Humans , Saudi Arabia , Male , Female , Cross-Sectional Studies , Adult , Diabetes Mellitus, Type 2/therapy , Diabetes Mellitus, Type 2/prevention & control , Diabetes Mellitus, Type 2/psychology , Middle Aged , Surveys and Questionnaires , Life Style , Young Adult , Aged , Adolescent
2.
Foods ; 10(2)2021 Feb 10.
Article in English | MEDLINE | ID: mdl-33578933

ABSTRACT

While the consumption of seaweed and seaweed-based products is very common amongst East Asian nations, forming a notable component of the daily diet, relatively very few studies have concerned the concentrations of heavy metals in these together with potential effects on human health. The present study analyses the concentrations of 17 elements in locally resourced seaweed, also assessing potential noncarcinogenic and carcinogenic risks. The samples were ground, homogenized, and quantified using the ICP-OES technique. It has been found that the essential elements K, Ca, Mg, Zn, and Na typically show concentrations somewhat greater than a number of potentially toxic metals, in particular, Cd, Pb, Ag, and As, with exceptions being Ni, Cr-VI, and Si. Statistical analysis indicates all of the latter to have similar origin, with increased concentration of these metals within the marine ecosystem. While the daily estimated intake of most metals is seen to be within the daily dietary allowance level recommended by various international organizations, the noncarcinogenic risk shows a value greater than unity, estimated via the hazard quotient. This indicates a potential for adverse effects to health arising from consumption of the sampled seaweed. The carcinogenic risk resulting from nonessential elements shows values greater than the United States Environmental Protection Agency (US-EPA) reference limit of 10-4. Considering the nonbiodegradability of heavy metals and metalloids and their potential accumulation in seaweed, there is need for critical examination of metal levels in the seaweeds obtained from the present study locations, together with the introduction of practices of removal of heavy metals via bio-adsorbent techniques.

3.
Phys Med ; 29(4): 374-8, 2013 Jun.
Article in English | MEDLINE | ID: mdl-22705397

ABSTRACT

Nitro blue tetrazolium (NBT) solution dosimeters were prepared and investigated based on radiation-induced reduction of NBT(2+). NBT solution dosimeters containing different concentrations of NBT dye from 1 to 5 mM were prepared in a solution of ethanol. The dosimeters were irradiated with 6 MV X-ray beam at doses up to 30 Gy. The dose sensitivity of NBT solution increases strongly with increase of concentrations of NBT dye. The dose response of NBT dosimeters increases remarkably by addition of various concentrations of sodium formate (0.5, 2.5 and 5 mM). It becomes more remarkable with increasing pH value of NBT-sodium formate dosimeters. The sensitivity of the solution increased fairly with increase of irradiation temperature, therefore, the response of the solutions has to be corrected under actual processing conditions. The stability of solution dosimeters after irradiation was very high up to 30 days.


Subject(s)
Nitroblue Tetrazolium/chemistry , Radiometry/methods , Radiotherapy Planning, Computer-Assisted/methods , Coloring Agents/chemistry , Hydrogen-Ion Concentration , Radiotherapy Dosage , Solutions , Temperature , X-Rays
4.
Spectrochim Acta A Mol Biomol Spectrosc ; 58(7): 1411-24, 2002 May.
Article in English | MEDLINE | ID: mdl-12083664

ABSTRACT

Some binary and ternary novel complexes of dioxouranium(VI) with 5-vinylsalicylaldehyde (VSH) have been prepared and characterized by various physico-chemical techniques. The amine exchange reactions of coordinated poly-Schiff bases in these complexes have been also carried out which give symmetrical tetradentate poly-Schiff base complexes. Metal exchange reaction of these dioxouranium(VI) complexes with copper(II) gives the corresponding Cu(II) complexes. Reaction of tetradentate poly-Schiff base complexes of Cu(II) so obtained with ZrCl4 gives heterobinuclear polymer complexes. Magnetic, electronic and IR spectral information commensurate that configurations of square planar copper(II) polymer complexes. All the polymer complexes are coloured and appear to be nonelectrolytes in DMF. The ligands behave as bi-(O, O) and tetradentate (N2, O2) donors. El-Sonbati equation was used to evaluate the symmetric stretching frequency from which the fU-O and fUO, UO- were calculated.


Subject(s)
Oxygen/chemistry , Polymers/chemistry , Spectrophotometry, Infrared/methods , Uranium , Aldehydes/chemistry , Biophysical Phenomena , Biophysics , Chlorides/chemistry , Copper/chemistry , Diamines/chemistry , Ions , Ligands , Models, Chemical , Organophosphorus Compounds/chemistry , Zirconium/chemistry
5.
Water Res ; 36(3): 633-7, 2002 Feb.
Article in English | MEDLINE | ID: mdl-11827325

ABSTRACT

Many industrial activities utilise formaldehyde as a key chemical in organic synthesis including: synthesis of special chemicals such as pentaerythritol and ethylene glycol, synthetic resins, paper products, medicinal products and drugs and others, too numerous to mention. Therefore, effluents arising from these applications may contain significant amounts of formaldehyde. In a biodegradation experiments of a wastewater sample containing formaldehyde ranging from 31.5 to 125 mg/l, residual formalin (a solution of formaldehyde gas in water) ranging from 40% to 85%, respectively, was found at the end of the run (16 d) showing the inhibition effect of formalin which increased with the increase in formalin concentration. The biodegradation of formalin decreased significantly at concentrations higher than 300 mg/l. A method to convert formaldehyde to an easily biodegradable substance is herein described. In the commercial manufacture of resins from phenol and formalin the reaction is never completely quantitative. As a result during the dehydration stage phenol and formalin are distilled from the wastewater. Phenol is toxic to several biochemical reactions. However, biological transformation of phenol to a non-toxic entity is possible through specialized microbes. Transformation of phenol is inhibited by the presence of formaldehyde. Biotransformation of phenol in a wastewater containing high concentrations of formaldehyde started shortly after treating the wastewater with calculated amounts of sodium sulphite. Sodium sulphite is believed to react with formaldehyde forming sodium formaldehyde bisulphite, which is not only non-toxic to microorganisms but also a biodegradable substance. From the DO measurements before and after the addition of sodium sulphite, the authors noticed that the dissolved oxygen in a wastewater containing formaldehyde is not affected by the addition of the calculated amount of sodium sulphite, which is just enough to consume the measured amount of formaldehyde in that wastewater.


Subject(s)
Disinfectants/metabolism , Formaldehyde/metabolism , Waste Disposal, Fluid/methods , Water Purification/methods , Biodegradation, Environmental , Disinfectants/chemistry , Formaldehyde/chemistry , Oxygen/chemistry , Sulfites/chemistry
6.
Acta Anaesthesiol Scand ; 44(6): 733-6, 2000 Jul.
Article in English | MEDLINE | ID: mdl-10903018

ABSTRACT

BACKGROUND: One puff of beclomethasone inhaler has been shown to reduce the incidence of sore throat following endotracheal intubation. The aim of this study was to determine the effect of a pharyngeal pack on the incidence of sore throat and whether tenoxicam-impregnated gauze pack significantly influenced the frequency of sore throat. METHODS: Eighty patients undergoing general anaesthesia for elective surgery of the nasal septum were evaluated. The anaesthetist sprayed the upper airway towards the trachea with one puff of beclomethasone inhaler (50 microg) before orotracheal intubation. Patients were randomly assigned to have either a 0.2% tenoxicam- or a 0.9% saline-impregnated gauze pack in the oropharynx during operation. They were evaluated for occurrence and severity of postoperative sore throat by direct questions 12-24 h after surgery. RESULTS: Four patients who experienced any symptoms in the tenoxicam group scored mild sore throat compared to 16 patients in the control group scoring mild, gradually developing moderate or severe sore throat (P<0.01). No drug-related side effects were observed. CONCLUSION: The intraoperative use of a tenoxicam-impregnated gauze pack is effective in reducing moderate or severe postoperative sore throat following the use of throat pack.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Pain, Postoperative/drug therapy , Pharyngitis/drug therapy , Piroxicam/analogs & derivatives , Administration, Inhalation , Administration, Topical , Adult , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Double-Blind Method , Female , Humans , Male , Middle Aged , Pharyngitis/etiology , Pharynx/physiology , Piroxicam/administration & dosage , Piroxicam/adverse effects , Piroxicam/therapeutic use , Prospective Studies
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