[Value of bone densitometry in the determination of vertebral mineral density in participants of the clean-up after Chernobyl accident]. / Znachenie osteodensitometrii v opredelenii kostnoi mineral'noi plotnosti pozvonochnika u uchastnikov likvidatsii avarii na ChAES.

Scanning osteodensitometry helped to study mineral saturation of lumbar vertebra in individuals who liquidated Chernobyl accident consequences. Bone mineral density appeared to depend on radiation dose obtained by the examinees. High risk of osteoporosis revealed in the examinees who participated in the liquidation in 1986. The authors stress that the examinees should be covered by the skeletal state monitoring possible only with osteodensitometry. The article justify that biphotonic scanning osteodensitometers are expedient in Health Care Centers for individuals who liquidated Chernobyl accident consequences.

[Osteopenic syndrome in liquidators of the aftereffects of the accident at the Chernobyl power plant]. / Osteopenicheskii sindrom u uchastnikov likvidatsii posledstvii avarii na Chernobyl'skoi atomnoi élektrostantsii.

Bone system was examined in 112 liquidators; in 71 of these osseous tissue density was studied by osseous densitometer using bienergetic x-ray absorptiometry and in 45 x-ray examinations, analyses of biochemical and hormonal parameters were carried out. Spinal painful syndrome was detected in 61 to 82% of the examinees. For analysis of densitometric and x-ray parameters the liquidators were divided into 2 groups: group 1 included those who worked at the power plant in 1986 (55%) and group 2 were those who worked there in 1987-1989. Radiation doses in group 1 reliably surpassed those in group 2 (p < 0.001). Bone mineral density in the lumbar vertebrae was significantly lower in group 1 as against group 2 and lower in both groups vs. controls. More than 5% osseous mineral loss was revealed in 73% of group 1 liquidators and in 43% of group 2 ones. Analysis of spinal roentgenograms in 45 liquidators showed a high incidence of negligible and moderately expressed osteoporosis without compression fractures of vertebral bodies: osteopenia signs were found in 87% of group 1 examinees complaining of pain in the spine and in 73% of group 2 examinees; signs of osteochondrosis and spondylosis were detected in 40% of group 1 and in 47% of group 2 subjects. Hence, a higher incidence of osteopenia in liquidators, more manifest condition and its higher detection rate in subjects exposed to higher radiation doses indicate a certain contribution of radiation factor to the development of the osteopenia syndrome in liquidators.

[Digital bone densitometry]. / Digital'naia osteodensitometriia.

Normal values of bone mineral composition were defined, based on examinations of 600 male and female volunteers of various age groups by digital roentgenodensitometry. The mineral compactness was found reduced in the patients with endocrine diseases, in subjects who participated in liquidation of the Chernobyl power plant accident aftereffects, and in those suffering from skeletal pains. The authors emphasize the value of digital roentgenodensitometry as a method for monitoring the efficacy of treatment of patients with endocrine diseases and chronic renal insufficiency.

[Bone tissue in patients with hyperprolactinemic hypogonadism]. / Sostoianie kostnoi tkani u bol'nykh s giperprolaktinemicheskim gipogonadizmom.

Sixteen women with hyperprolactinemia were examined for Ca metabolism, osseous metabolism, mineral saturation of bone tissue in the thoracic portion of the spine and radius. Lowered mineral saturation of the thoracic vertebrae was detected in 69% of the examinees, that of the distal segment of the radius in 44%. Reduction of the mineral saturation of the spine was in negative correlation with the blood prolactin level and length of amenorrhea. No changes in the bone resorption biochemistry or Ca metabolism were detected. A marked reduction of blood osteocalcin level that reflects osteoblast function was detected, its blood concentration being in negative correlation with prolactin level. No relationships between mineral saturation of bone tissue, prolactin, and osteocalcin, on the one hand, and blood estradiol level, on the other, were observed. These data suggest that osteopathy in hyperprolactinemic hypogonadism is due to reduced bone formation and not to reduced estradiol production.

[Comparison of diagnostic methods for osteoporosis in endogenous hypercorticism]. / Sravnitel'naia kharakteristika metodov diagnostiki osteoporoza pri éndogennom giperkortitsizme.

The informative value of diagnosis of osteoporosis in 53 patients with Itsenko-Cushing disease was assessed by visual estimation of radiograms of the axial skeleton, standard x-ray densitometry of the phalanges of the thumbs and single-photon absorptiometry of the distal parts of antebrachial bones. Diagnosis of osteoporosis and its evaluation over time were shown to be accurate in combination of visual assessment of radiograms of the axial skeleton with standard x-ray densitometry of the peripheral parts of the skeleton. Single-photon absorptiometry revealed no decrease in the level of the osseous mineral in the forearm of patients with endogenous hypercorticoidism. In the majority of female patients this indicator even exceeded the normal age value. Possible causes of this phenomenon are under discussion.

[Skeletal scintigraphy in hemangioma of the bones]. / Stsintigrafiia skeleta pri gemangiomakh kostei.

The results of scintigraphic investigations of the skeleton of 76 bone hemangioma patients were analyzed to study the informative value of this type of investigation and to determine the efficacy of its use during establishing diagnosis and dynamic observation. The probability of detection of bone hemangiomas using scintigraphy of the skeleton with 99m Tc labeled osteotropic agents was shown to be in direct relation to the biological activity of hemangioma, its site and resolution of radiodiagnostic apparatus. The utilization of scintigraphy of the skeleton in addition to x-ray investigation permits clarification of the nature of lesion (benign or malignant), the biological activity of hemangiomas, control of the time course of a pathological process and efficacy of therapy of biologically active hemangiomas.

[X-ray features of fibrous osteodystrophy and osteomalacia in patients with chronic renal insufficiency under present-day treatment]. / Rentgenologicheskie osobennosti fibroznoi osteodistrofii i osteomaliatsii u bol'nykh s khronicheskoi pochechnoi nedostatochnost'iu v usloviiakh sovremennogo ee lecheniia.

The authors present the results of clinicoroentgenological and biochemical investigations in 102 patients with chronic renal insufficiency after hemodialysis and in 76 patients after kidney transplantation. The nature of secondary hyperparathyroid fibrous osteodystrophy and osteomalacia as main symptoms of nephrogenic osteodystrophy (NO), their interrelation and correlation are analysed. Of 178 patients pathological changes of the bone system were revealed in 94 (52.9%). The combination of fibrous osteodystrophy and osteomalacia (22%) is regarded as a contraindication for parathyroidectomy. Effective kidney transplantation does not prevent NO though its specificity changes: osteomalacia is more marked, osteonecrosis and soft tissue calcification are more common. The chief method of radiodiagnosis of NO is routine radiography of the skeleton supplemented by small feature contact radiography and x-ray image color analysis on the UAR and TELEVAN TV units. Comparative roentgenodensitometry of the bones and CT of the parathyroid glands contributed to obtaining objective information but was of applied value.