Correlation study among water quality parameters an approach to water quality management.

To find out an approach to water quality management through correlation studies between various water quality parameters, the statistical regression analysis for six data points of underground drinking water of different hand pumps at J. P. Nagar was carried out. The comparison of estimated values with W.H.O drinking water standards revealed that water of the study area is polluted with reference to a number of physico-chemical parameters studied. Regression analysis suggests that conductivity of underground water is found to be significantly correlated with eight out of twelve water quality parameters studied. It may be suggested that the underground drinking water quality at J. P. Nagar can be checked very effectively by controlling the conductivity of water. The present study may be treated one step forward towards the water quality management.

Personality pattern of parents of mentally retarded children.

Parents of fifty mentally retarded children were studied for their personality pattern with the help of Middlesex Hospital Questionnaire. In fathers and mothers separately, none of the personality traits were observed to vary at statistically significant level in relation to the degree of retardation in their child, but both the parents of mildly retarded children obtained higher score on scale of anxiety, phobia and depression. Analysis of different factors when compared for fathers and mothers together, revealed a higher degree of neurotic traits in mothers.

LH, FSH responses to GnRH in lepromatous leprosy

Significant rise in serum LH and FSH and a fall in serum testosterone have been reported in lepromatous leprosy (Dash, Samuel, Kaur, Datta and Rastogi 1978). This is consistent with extensive damage to the tubular and interstitial cells of the testes (Grabstald and Swan 1952; Desican and Job 1972; Bernard and Veraquez 1973; Samuel, Kumar, Kaur, Kannan, Dash, Rastogi and Datta 1978).

Evaluation of male gonadal function in leprosy

Impotency, sterility, loss of libido, loss of sexual hair and gynecomastia are well documented in patients suffering from leprosy. They occur with greater frequency in lepromatous leprosy as compared to dimorphous and tuberculois types.

Effect of estrogens on thyroid function. I. Alterations in rhesus plasma thyrotropin and its kinetics.

The circulating levels of TSH, its metabolism, and its response to synthetic TRH were studied in five euthyroid menstruating rhesus monkeys before and during treatment with estradiol monobenzoate (E2B, 50 microgram/kg BW/day sc). The pre-E2B treatment mean plasma TSH level was 1.4 +/- 0.12 (SE) microunit/ml. A significant increase in mean plasma TSH (P less than 0.01) to 1.54 +/- 0.29 microunit/ml was observed as early as 48 h after intiation of E2B treatment; it continued to rise progressively to day 28 when it plateaued around a mean concentration of 3 microunit/ml. It normalized within 10 days after cessation of E2B therapy. After iv TRH (5 microgram/kg BW), a consistent rise in plasma TSH was observed before and on days 11 and 56 of E2B therapy. The peak TSH level and maximum rise over the basal level (deltaTSH) during the three tests were not significantly different. During E2B therapy there were remarkable changes in TSH kinetics. These alterations included a significant decrease (P less than 0.01) in metabolic clearance rate, contraction of the distribution space, and expansion of the extrapituitary TSH pool, but there was no appreciable change in TSH production rate. Although a definite trend towards the above alterations was discernible on day 17 of treatment, they were well established by day 66. These data suggest that the estrogen-induced rise in circulating TSH was caused mainly by decreased degradation and not by increased production.