ABSTRACT
To specify the role porphyrins play in the development of diffuse liver injuries, 53 patients with alcohol-induced liver injuries were examined. Of these, 17 patients manifested marked derangement of porphyrin metabolism. As a result of clinico-biochemical, immunological and morphological research methods, it is established that marked derangement of porphyrin metabolism manifesting itself in porphyrin deposition in hepatocytes and in the high level of uro and coproporphyrinuria is associated with the development of autoimmune reactions towards liver-specific lipoprotein, which determines the development of the grave forms of liver injury in patients who abuse alcohol.
Subject(s)
Liver Diseases, Alcoholic/metabolism , Porphyrins/physiology , Adult , Coproporphyrins/urine , Female , Humans , Liver Diseases, Alcoholic/immunology , Male , Middle Aged , Uroporphyrins/urineABSTRACT
Cardiovascular system parameters were measured in 80 patients with renovascular hypertension using resting and bicycle exercise readings of tetrapolar chest rheography. The findings were indicative of various defects in central hemodynamics. Signs of subclinical initial stage of cardiac insufficiency were revealed in 57.5% of cases. Cardiovascular reserves were reduced in patients operated on fading with increasing duration of the disease. Labor prognosis appeared more favorable in operated on patients with good hypotensive effect of the surgery.
Subject(s)
Hemodynamics , Hypertension, Renovascular/rehabilitation , Work Capacity Evaluation , Adult , Exercise Test , Female , Humans , Hypertension, Renovascular/surgery , Male , Middle Aged , Plethysmography, Impedance , Postoperative PeriodSubject(s)
Hepatitis B/immunology , Hepatitis, Chronic/immunology , Liver Cirrhosis/immunology , T-Lymphocytes, Regulatory/immunology , Adolescent , Adult , Aged , Female , Humans , Immune Tolerance , Male , Middle AgedABSTRACT
Fascial-adipose tissue sheaths of the superior mesentery artery consist of: a proper fibrous tunic separated by a paravasal fissura from the external layer of the arterial wall; an adipose tissue coupling with vascular and nervous plexus--around the vessels, and a fascial case which isolates the adipose tissue coupling from the surrounding adipose tissue. The fascial case is more dense around the trunk and less dense around the branches of the superior mesentery artery. The work presents the data of the development of the fascial-adipose tissue sheaths and their age-dependent changes which result in a considerable exhaustion of these sheaths at an old age, in deposition of adipose tissue between the fascial plates. The thickness of the fascial-adipose tissue sheath of the superior mesentery artery varies, depending on age, from 5 to 12 mm. It is considerably more developed than similar fascial-adipose tissue sheaths of the celiac trunk and the inferior mesentery artery, is of great applied importance for novocain blockade of the paraarterial nervous plexus.
