1.
Cardiovasc J Afr
; 24(9-10): e4-7, 2013 Oct 23.
Article
in English
| MEDLINE
| ID: mdl-24337243
ABSTRACT
Osteogenesis imperfecta (OI) is a heritable disorder of the connective tissue. Cardiovascular involvement is rare, related mainly to aortic valve regurgitation. Open-heart surgery in these patients is associated with increased morbidity and mortality rates as a result of tissue friability and bone brittleness as well as platelet dysfunction. We present a patient with OI who underwent successful aortic valve replacement with a mini-sternotomy approach.